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182 Pages·2009·3.7 MB·English

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ith the abbreviation of Asian Journal of Andrology—"AJA" being the basic
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in the following decades!
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2211330011--0066__AAJJAA 33AAPPFFAA__1100tthhAAnnnniivv RRJJFFPP..iinndddd 11 1133//88//0099 1144::2299::0044
Asian Journal of
Andrology
Volume 11, Number 5 (Supplement)
October 2009
The Proceedings
of
the Third Asia-Pacifi c Forum on Andrology
10–13 October 2009, Nanjing, China
Environment, Life Style & Genetic/Epigenetic Factors
and Men’s Health
 2009, AJA, SIMM & SJTU. All rights reserved 1008-682X/09
1
2009年增刊 出版许可证（2009）第093号
Contents
Welcome Message from Chairman of 3APFA 4
Welcome Message from Chairman of Local Committee of 3APFA 5
Organizations 6
Short CV of Keynote Speakers 8
Agenda 13
Programme 15
Plenary/Symposium Lectures & Oral Presentations/Special Session for Chinese 25
Oral Presentation
Poster Presentaion 96
Author Index 173
Instruction for Authors of Asian Journal of Andrology 180
The Third Asia-Pacific Forum on Andrology
October 10–13, Nanjing, China
Andrology
Asian Journal of
npg nature publishing group
Volume 11, Issue 5, Supplement, October 2009, Published on October 1, 2009
Honorary Editors-in-Chief Deputy Editor-in-Chief Ji-Chuan Zhu, China Rong-Rong Ma, China
Shao-Zhen Qian, China David J Handelsman, Australia Dan-Qing Ren, China
Jie-Ping Wu, China Editorial Director Hui Zhang, China
Associate Editors-in-Chief Qin-Zhu Zheng, China
Editor-in-Chief Sujoy K Guha, India Executive Editor for this issue
Yi-Fei Wang, China Je Jong Kim, Korea Science Editors Hui Zhang, China
Akihiko Okuyama, Japan Ling-Yan Ji, China
REGIONAL J Anton Grootegoed, Netherlands Yi-Qun Gu, China Yuan-Chang Yan, China
COORDINATORS Zhi-Ping Gu, China Gerhard Haidl, Germany Zheng-Wei Yang, China
Ying-Lu Guo, China Aucky Hinting, Indonesia Ching-Hei Yeung, Germany
Asia Wayne JG Hellstrom, USA Russell Campbell Jones, Australia
Premendu P Mathur, India Barry Hinton, USA Sae Chul Kim, Korea CORRESPONDING EDITORS
Ilpo Huhtaniemi, Finland Dolores J Lamb, USA BOARD
Australia Yu Jiang, China Will M Lee, Hongkong, China Salman Azhar, USA
De-Yi Liu, Australia Niels Jorgensen, Denmark Ching-Shwun Lin, USA Elias Castanas, Greece
F-M Köhn, Germany Alvin Y Liu, USA Adel Hassan Elbeheiry, Egypt
Africa Iwan Lewis-Jones, UK Peter Yiwen Liu, Australia Paolo Emiliozzi, Italy
Ralf Henkel, South Africa Bruno Lunenfeld, Israel Yi-Xun Liu, China Tibet Erdogru, Turkey
Soon Chye Ng, Singapore Tom Futai Lue, USA Jiao-Ti Huang, USA
Europe Marie-Claire Orgebin-Crist, USA Kamal Zaki Mahmoud, Egypt Yu-Feng Huang, China
Louis Gooren, The Netherlands Wolf-Bernhard Schill, Germany William J Moorman, USA Zheng Li, China
Roger Short, Australia Toshiaki Noce, Japan Hui Jiang, China
North America Ronald S Swerdloff, USA Jae-Seung Paick, Korea Young Chan Kim, Korea
Chawnshang Chang, USA Fred C W Wu, UK Gedalia Paz, Israel Shahriar Koochekpour, USA
She-Pu Xue, China Gail S Prins, USA Sang Kon Lee, Korea
ADVISORY BOARD Brian Peter Setchell, Australia Somboon Leungwattanakij, Thailand
EDITORIAL BOARD Jia-Hao Sha, China N K Lohiya, India
Chairmen P Ganesan Adaikan, Singapore David Sokal, USA Nian-Qing Lu, China
David de Kretser, Australia FX Arif Adimoelja, Indonesia Guang-Huan Sun, Taiwan, China Okabe Masaru, Japan
Yong-Lian Zhang, China Ashok Agarwal, USA Qing-Yuan Sun, China Moira Kathleen O’ Bryan, Australia
R John Aitken, Australia M Ismail M Tambi, Malaysia Steven M Schrader, USA
Members Anna-Maria Andersson, Denmark Hui Meng Tan, Malaysia Zhou-Jun Shen, China
Dimitri A Adamopoulos, Greece Susan H Benoff, USA Goh Hng Hang Victor, USA Teruaki Iwamoto, Japan
Gordon Baker, Australia Joseph C Cappelleri, USA Guo-Min Wang, China Run Wang, USA
Arnold M Belker, USA Wai-Yee Chan, USA Yi-Xin Wang, China Zhong-Cheng Xin, China
Hector Chemes, Argentina Junichi Fujii, Japan Patrick YD Wong, Hongkong, China Yuan-Cheng Xu, China
Trevor G Cooper, Germany Robert Howard Getzenberg, USA Shu-Jie Xia, China Bo Yang, China
Rune Eliasson, Sweden David John Grignon, USA Hong Xiao, China
Aleksander Giwercman, Sweden Sidney Ray Grimes, USA Chen Xu, China
Sponsored by the Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences and Shanghai Jiao Tong University (SJTU).
Granted by Publishing Foundation of Chinese Academy of Sciences, and National Natural Science Foundation of China (NSFC).
Supervised by Chinese Academy of Sciences.
Published jointly by the Editorial Office, Asian Journal of Andrology and Nature Publishing Group.
Printed by Shanghai Tu-Yu Printing House, 28 Lane 23 Yin-Gao Road, Shanghai 200439, China.
Edited by the Editorial Office, Asian Journal of Andrology, Room 302, Building 16, 294 Tai-Yuan Rd, Shanghai 200031, China. E-mail: [email protected];
Tel: [phone]; Fax: [phone].
Disclaimer The Publisher, Society and Editors cannot be held responsible for errors or any consequences arising from the use of information contained in this
journal; the views and opinions expressed do not necessarily reflect those of the Publisher, Society and Editors, neither does the publication of advertisements
constitute any endorsement by the Publisher, Society and Editors of the products advertised.
Copyright © 2009 Asian Journal of Andrology, SIMM and SJTU.
ISSN 1008-682X EISSN 1745-7262 CN 31-1795/R
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4
Welcome Message from Chairman of 3APFA
Dear Colleagues,
On behalf of the Asian Journal of Andrology (AJA) and the Organizing Committee,
I wish to extend to everyone with great concerns about men's health my cordial
invitation to attend the Third Asia-Pacific Forum on Andrology (3APFA), in
conjunction with the Tenth Anniversary Celebration of AJA, to be held on October
10–13, 2009, Nanjing, China.
The theme of this Forum is “Environment, Life Style & Genetic/Epigenetic Factors
and Men's Health”, endeavoring to explore the profundity and diversity of the
contributing factors to men's health.
The Scientific Committee, under the guidance of the Advisory Committee, designed
a comprehensive scientific programme concentrating on one vital issue and
embracing a large range of important aspects including:
1 Men's Health: Global and Regional Perspectives
2 Sperm Biology and Fertilization
3 Male Infertility and Assisted Reproductive Technology
4 Male Sexual Dysfunction
5 Male Ageing, Androgen Deficiency and Therapy
6 Prostate Diseases and Prevention, Diagnosis & Treatment of Prostate Cancer
7 Environment Hazards to Men's Health
8 Prevention of Life-threatening STDs/HIV Infections
9 Prevention of Overpopulation and Male Contraception
10 Alternative/Traditional Medicine and Andrology
With an aim of bridging the communication between the lab and the clinic, we deeply believe that the Forum
deserves the attention from not only basic scientists but also clinicians in the field of andrology.
Besides the traditional plenary lectures and symposia we have innovatively introduced in the programme "Panel
Discussion on Holistic Concept on Men's Health, Health Determinants and Health Promotion" and "Public
Consultation" sessions. "Panel Discussion" session allows an all-dimensional discussion among scientists, clinic
doctors, public, media, and policy makers. "Public Consultation" session brings doctors out of the clinics to the
public hall and allows the public to touch more knowledge on men's health in a relaxed and friendly atmosphere. In
its Tenth Anniversary Celebration, AJA will express a great deal of gratitude to people who support and contribute
to its development in various ways, and will review the past, summarize the present and shape the future.
In addition, there are several satellite workshops with topics on male infertility, erectile dysfunction, prostate
disease, andrology in ARTs, LOH, etc. A specific session for WHO standard semen analysis manual (5th edition) will
also be organized during the Forum.
We look forward to welcoming you to the 3APFA, Nanjing, China, which no doubt will be a memorable occasion for
fruitful interchanges of ideas and the development of long-lasting friendship in the coming years.
With Best Regards,
Prof. Yi-Fei Wang
Chairman of Third Asia-Pacific Forum on Andrology
Executive President of Asian Society of Andrology
Editor-in-Chief of Asian Journal of Andrology
5
Welcome Message from Chairman of Local Organization Committee of 3APFA
Dear Colleagues:
On behalf of the Local Organizing Committee, I sincerely invite you to attend the Third
Asia-Pacific Forum on Andrology (3APFA), in conjunction with the Tenth Anniversary
Celebration of Asian Journal of Andrology, which will be held in Nanjing, China on
October 10–13, 2009.
The theme of the forum is "Invironment, Lifestyle & Genetic/Epigenetic Factors and
Men's Health". Ten topics covering hot issues in current research field of men's health
have been set up and several internationally reputable experts in related fields will
be invited to present their views on these aspects. During the Forum, several satellite
meetings on andrological surgery, laboratory research of Assisted Reproductive
Technology (ART) and other popular andrological aspects will take place and Chinese
Session will be held particularly for Chinese andrologists. Since 2009 is the 10th Anniversary of Asian Journal of
Andrology (AJA), the celebration ceremony will be held during the Forum. As the host, we are honored to take
this opportunity to co-organize this forum with Shanghai Institute of Materia Medica, CAS and Shanghai Jiao Tong
University. We do believe that this meeting will offer a platform for fruitful exchanges and communication among
researchers all over the world.
Nanjing, locating at the foot of Zhongshan Mountain, near Yangtze River, is one of China's historical and cultural
cities. October is the clear and crisp days of autumn in Nanjing, with the orange osmanthus blossoming with
fragrance. During the meeting, the Local Organizing Committee will carefully arrange rich and colorful social
activities, allowing you to enjoy the beautiful natural scenery and city culture landscape besides the academic
exchanges. We believe Nanjing, as the ancient capital of the Six Dynasties, will give you an indelible impression.
The whole Local Organizing Committee of 3APFA are looking forward to meeting you in Nanjing, China!
With Best Regards,
Prof. Jia-Hao Sha
Chairman of Local Organizing Committee of Third Asia-Pacific Forum on Andrology
Director of Laboratory of Reproductive Medicine, Nanjing Medical University
6
3APFA Organizations Members
Bin Chen (Shanghai) Yu-Gui Cui (Nanjing)
Min Gu (Nanjing) Xiao-Yan Huang (Nanjing)
Honorary Presidents Shao-Zhen Qian (China) Ran Huo (Nanjing) Ling-Yan Ji (China)
Jie-Ping Wu (China) Jing Leng (Nanjing) Zheng Li (Shanghai)
Forum Chairman Yi-Fei Wang (China) Nian-Qing Lu (Nanjing) Dan-Qing Ren (Shanghai)
Hui Wang (Nanjing) Shou-Lin Wang (Nanjing)
International Advisory Committee Hui Zhang (Shanghai)
Chairman David de Kretser (Australia)
Vice-Chairman Ying-Lu Guo (China) Program Committee
Members Chairmen Qi Chen (Nanjing)
P Ganesan Adaikan (Singapore) Hector E Chemes (Argentina) Yi-Fei Wang (Shanghai)
Guo-Qiang Chen (China) Jian Ding (China)
Rune Eliasson (Sweden Aleksander Giwercman (Sweden) Members
Louis Gooren (the Netherlands) J Anton Grootegoed (the Netherlands) Zhi-Ming Cai (Shenzhen) Chun-Hua Deng (Guangzhou)
Sujoy K Guha (India) Tim B Hargreave (UK) Tian-Hua Huang (Shantou) Yi-Ran Huang (Shanghai)
Wayne JG Hellestrom (USA) Sae-Chul Kim (Korea) Yu-Feng Huang (Hangzhou) Hui Jiang (Beijing)
Yi-Xun Liu (China) Bruno Lunenfeld (Israel) Zhou-Jun Shen (Shanghai) Jun-Ping Shi (Shenyang)
Wolf-Bernhard Schill (Germany) Roger Short (Australia) Yin-Hao Sun (Shanghai) Xiao-Feng Wang (Beijing)
Ronald S Swerdloff (USA) Lin-Fang Wang (China) Yuan-Cheng Xu (Nanjing) Bo Yang (Hangzhou)
Fred C Wu (UK) Yong-Lian Zhang (China) Zheng-Wei Yang (Nanchong)
Scientific Committee Secretariat
Chairmen David J Handelsman (Australia)
Ji-Chuan Zhu (China) Secretary General Qin-Zhu Zheng (Shanghai)
Vice-Chairmen Premendu P Mathur (India) Vice-Secretary General Hui Zhu (Nanjing)
Xin-Ru Wang (China)
Members
Members Ling-Yan Ji (Shanghai) Rong-Rong Ma (Shanghai)
Arif Adimoelja (Indonesia) R John Aitken (Australia) Dan-Qing Ren (Shanghai) Yi-Fei Tian (Shanghai)
De-Gui Chen (China) Hugh William Gordon Baker (Australia) Lei Wang (Nanjing) Hui Zhang (Shanghai)
Joseph C Cappelleri (USA) Chawnshang Chang (USA)
Zhao-Dian Chen (China) Trevor G Cooper (Germany) Organized By Shanghai Institute of Materia Medica, Chinese Academy of Sciences (SIMM, CAS)
Yi-Qun Gu (China) Ralf Henkel (South Africa) Shanghai Jiao Tong University (SJTU)
He-Feng Huang (China) Je Jong Kim (Korea) Nanjing Medical University (NMU)
De Yi Liu (Australia) Jia-Yin Liu (China) Hosted by Asian Journal of Andrology, SIMM, CAS & SJTU
Peter Liu (Australia) Guang-Xiu Lu (China) Laboratory of Reproductive Medicine, NMU
Tom Lue (USA) Akihiko Okuyama (Japan) Asian Society of Andrology (ASA)
Jie Qiao (China) Farid Saad (Germany) Supported by World Health Organization (WHO)
M Ismail M Tambi (Malaysia) Hui-Meng Tan (Malaysia) International Society of Andrology (ISA)
Goh Victor (USA) Run Wang (USA) Chinese Academy of Sciences (CAS)
Yi-Xin Wang (China) Shu-Jie Xia (China) Chinese Society of Reproductive Medicine
Zhong-Cheng Xin (China) Chen Xu (China) Shanghai Family Planning and Reproductive Health Society
Wei Zhang (China) Yuan-Fang Zhang (China) Shanghai Key Laboratory for Reproductive Medicine
Xue-Jian Zhao (China) Shanghai Key Laboratory for Molecular Andrology
Institue of Urology, Shanghai Jiao Tong University
Local Organizing Committee Department of Urology, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Chairman Jia-Hao Sha (Nanjing) Department of Urology, Shanghai Changhai Hospital, The Second Military Medical University
Vice-Chairmen Qin-Zhu Zheng (Shanghai) Shanghai Huashan Hospital, Fudan University
Shanghai Haike Family Medicine Technology Consulting Ltd.
Zuo-Min Zhou (Nanjing)
7
3APFA Organizations Members
Bin Chen (Shanghai) Yu-Gui Cui (Nanjing)
Min Gu (Nanjing) Xiao-Yan Huang (Nanjing)
Honorary Presidents Shao-Zhen Qian (China) Ran Huo (Nanjing) Ling-Yan Ji (China)
Jie-Ping Wu (China) Jing Leng (Nanjing) Zheng Li (Shanghai)
Forum Chairman Yi-Fei Wang (China) Nian-Qing Lu (Nanjing) Dan-Qing Ren (Shanghai)
Hui Wang (Nanjing) Shou-Lin Wang (Nanjing)
International Advisory Committee Hui Zhang (Shanghai)
Chairman David de Kretser (Australia)
Vice-Chairman Ying-Lu Guo (China) Program Committee
Members Chairmen Qi Chen (Nanjing)
P Ganesan Adaikan (Singapore) Hector E Chemes (Argentina) Yi-Fei Wang (Shanghai)
Guo-Qiang Chen (China) Jian Ding (China)
Rune Eliasson (Sweden Aleksander Giwercman (Sweden) Members
Louis Gooren (the Netherlands) J Anton Grootegoed (the Netherlands) Zhi-Ming Cai (Shenzhen) Chun-Hua Deng (Guangzhou)
Sujoy K Guha (India) Tim B Hargreave (UK) Tian-Hua Huang (Shantou) Yi-Ran Huang (Shanghai)
Wayne JG Hellestrom (USA) Sae-Chul Kim (Korea) Yu-Feng Huang (Hangzhou) Hui Jiang (Beijing)
Yi-Xun Liu (China) Bruno Lunenfeld (Israel) Zhou-Jun Shen (Shanghai) Jun-Ping Shi (Shenyang)
Wolf-Bernhard Schill (Germany) Roger Short (Australia) Yin-Hao Sun (Shanghai) Xiao-Feng Wang (Beijing)
Ronald S Swerdloff (USA) Lin-Fang Wang (China) Yuan-Cheng Xu (Nanjing) Bo Yang (Hangzhou)
Fred C Wu (UK) Yong-Lian Zhang (China) Zheng-Wei Yang (Nanchong)
Scientifi c Committee Secretariat
Chairmen David J Handelsman (Australia)
Ji-Chuan Zhu (China) Secretary General Qin-Zhu Zheng (Shanghai)
Vice-Chairmen Premendu P Mathur (India) Vice-Secretary General Hui Zhu (Nanjing)
Xin-Ru Wang (China)
Members
Members Ling-Yan Ji (Shanghai) Rong-Rong Ma (Shanghai)
Arif Adimoelja (Indonesia) R John Aitken (Australia) Dan-Qing Ren (Shanghai) Yi-Fei Tian (Shanghai)
De-Gui Chen (China) Hugh William Gordon Baker (Australia) Lei Wang (Nanjing) Hui Zhang (Shanghai)
Joseph C Cappelleri (USA) Chawnshang Chang (USA)
Zhao-Dian Chen (China) Trevor G Cooper (Germany) Organized By Shanghai Institute of Materia Medica, Chinese Academy of Sciences (SIMM, CAS)
Yi-Qun Gu (China) Ralf Henkel (South Africa) Shanghai Jiao Tong University (SJTU)
He-Feng Huang (China) Je Jong Kim (Korea) Nanjing Medical University (NMU)
De Yi Liu (Australia) Jia-Yin Liu (China) Hosted by Asian Journal of Andrology, SIMM, CAS & SJTU
Peter Liu (Australia) Guang-Xiu Lu (China) Laboratory of Reproductive Medicine, NMU
Tom Lue (USA) Akihiko Okuyama (Japan) Asian Society of Andrology (ASA)
Jie Qiao (China) Farid Saad (Germany) Supported by World Health Organization (WHO)
M Ismail M Tambi (Malaysia) Hui-Meng Tan (Malaysia) International Society of Andrology (ISA)
Goh Victor (USA) Run Wang (USA) Chinese Academy of Sciences (CAS)
Yi-Xin Wang (China) Shu-Jie Xia (China) Chinese Society of Reproductive Medicine
Zhong-Cheng Xin (China) Chen Xu (China) Shanghai Family Planning and Reproductive Health Society
Wei Zhang (China) Yuan-Fang Zhang (China) Shanghai Key Laboratory for Reproductive Medicine
Xue-Jian Zhao (China) Shanghai Key Laboratory for Molecular Andrology
Institue of Urology, Shanghai Jiao Tong University
Local Organizing Committee Department of Urology, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Chairman Jia-Hao Sha (Nanjing) Department of Urology, Shanghai Changhai Hospital, The Second Military Medical University
Vice-Chairmen Qin-Zhu Zheng (Shanghai) Shanghai Huashan Hospital, Fudan University
Shanghai Haike Family Medicine Technology Consulting Ltd.
Zuo-Min Zhou (Nanjing)