Stem Cells, Craniofacial Development and Regeneration

560 Pages·2013·8.841 MB·English

by  George T.J. Huang, Irma Thesleff

STEM CELLS IN
CRANIOFACIAL
DEVELOPMENT
AND REGENERATION
STEM CELLS IN
CRANIOFACIAL
DEVELOPMENT
AND REGENERATION
Edited by
GEORGE T.-J. HUANG, D.D.S., M.S.D., D.Sc.
Professor, Department of Bioscience Research
College of Dentistry
The University of Tennessee Health Science Center
Memphis, Tennessee
IRMA THESLEFF, D.D.S., Ph.D.
Professor, Developmental Biology Program
Institute of Biotechnology
University of Helsinki
Helsinki, Finland
A JOHN WILEY & SONS, INC., PUBLICATION
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LibraryofCongressCataloging-in-PublicationData:
Stemcellsincraniofacialdevelopmentandregeneration/editedbyGeorge
T.-J.Huang,IrmaThesleff.
p.cm.
Includesbibliographicalreferencesandindex.
ISBN978-1-118-27923-6(cloth)
1. Regeneration(Biology).2. Boneregeneration.3. Guidedbone
regeneration.4. Stemcells.I.Huang,GeorgeT.-J.II.Thesleff,Irma.
QH499.S8162013
571.8(cid:2)89–dc23
2012028577
PrintedinSingapore
10987654321
CONTENTS
Contributors xi
Preface xv
PART I DEVELOPMENT AND REGENERATION
OF CRANIOFACIAL TISSUES AND ORGANS
1 Molecular Blueprint for Craniofacial Morphogenesis
and Development 3
PaulA.Trainor
2 Cranial Neural Crest Cells in Craniofacial Tissues and Organs 31
CarolinaParadaandYangChai
3 Craniofacial Intramembranous Bone Development
and Regeneration 51
DavidP.RiceandRitvaRice
4 Temporomandibular Joint Development 71
ShupingGuandYiPingChen
5 Craniofacial Muscle Development 87
RobertG.Kelly
6 Tooth Morphogenesis and Renewal 109
MariaJussila,EmmaJuuri,andIrmaThesleff
v
vi CONTENTS
7 Reptilian Tooth Regeneration 135
JoyM.Richman,JohnA.Whitlock,andJohnAbramyan
8 Tooth Root Development 153
BrianL.Foster,FranciscoH.NocitiJr.,
andMarthaJ.Somerman
9 Systems Biology of Early Tooth Development 179
DanielJ.O’Connell,JoshuaW.K.Ho,andRichardL.Maas
PART II STEM CELLS AND THEIR NICHES
IN CRANIOFACIAL TISSUES
10 Stem Cells, Induced Pluripotent Stem Cells, and Their
Differentiation to Specified Lineage Fates 205
GeorgeT.-J.Huang,Xiao-YingZou,XingYan,KyleJ.Hewitt,YuliaShamis,
andJonathanA.Garlick
11 Bone Marrow Mesenchymal Stem Cells 223
SongtaoShiandStanGronthos
12 Adipose Tissue–Derived Stem Cells and Their Regeneration
Potential 241
JeffreyGimble,MaryamRezaiRad,andShaomianYao
13 Skeletal Muscle Stem Cells: Their Origin and Niche Factors 259
JohannesW.VondenHoffandSanderGrefte
14 Stem Cells in Salivary Gland Development and Regeneration 271
IsabelleM.A.LombaertandMatthewP.Hoffman
15 Stem and Progenitor Cells of Dental and Gingival Tissue Origin 285
ChristianMorsczeck,GeorgeT.-J.Huang,andSongtaoShi
16 Regulation and Differentiation Potential of Dental
Mesenchymal Stem Cells 303
LeiWang,ChristianMorsczeck,StanGronthos,
andSongtaoShi
17 An Incisive Look at Stem Cells: The Mouse Incisor
as an Emerging Model for Tooth Renewal 315
FredericMichon,AndrewH.Jheon,KerstinSeidel,
andOphirD.Klein
18 Mesenchymal Stem Cell Niches in Rodent Tooth Pulp 329
JifanFengandPaulT.Sharpe
CONTENTS vii
PART III STEM CELL–MEDIATED CRANIOFACIAL TISSUE
BIOENGINEERING
19 Bone Bioengineering: Scaffolds, Growth Factors, and Stem Cells 341
ChristopherS.D.Lee,ChristopherD.Hermann,RolandoGittens,
ReneOlivares-Navarrete,ZviSchwartz,andBarbaraD.Boyan
20 Craniofacial Tissue Bioengineering and Regeneration
by Endogenous Stem Cells 367
NanJiang,MoChen,ChangHunLee,JianZhou,MildredC.Embree,
KimiKong,ChokoCho,AvitalMendelson,YingZheng,HeminNie,
andJeremyJ.Mao
21 Stem Cell–Based Bioengineering of Craniofacial Bone 379
DavidD.Lo,DanielT.Montoro,MonicaGrova,JeongS.Hyun,
MichaelT.Chung,DerrickC.Wan,andMichaelT.Longaker
22 Muscle Tissue Engineering Approaches 395
JohannesW.VondenHoffandSanderGrefte
23 Engineering of Dental Tissues: Scaffolds and Preclinical Models 409
NaYu,AdelinaPlachokova,FangYang,X.FrankWalboomers,
andJohnA.Jansen
24 Whole-Tooth Engineering and Cell Sources 431
L.Keller,S.Kuchler-Bopp,andHerve´ Lesot
25 Bioengineering of Functional Teeth 447
TakashiTsuji
26 Pulp and Dentin Regeneration 461
MisakoNakashimaandGeorgeT.-J.Huang
27 Bioengineering of Roots and Periodontal Tissues 485
SonglinWang,GangDing,FulanWei,andYiLiu
28 Periodontal Bioengineering Strategies: The Present Status
and Some Developing Trends 501
Fa-MingChenandYanJin
Index 525
CONTRIBUTORS
John Abramyan, Ph.D., Postdoctoral Fellow, Department of Oral Health Sciences,
Life Sciences Institute, University of British Columbia, Vancouver, British
Columbia, Canada
Barbara D. Boyan, Ph.D., Professor, Price Gilbert, Jr. Chair in Tissue Engineering,
Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of
Technology, Atlanta, Georgia
Yang Chai, D.D.S., Ph.D., George and MaryLou Boone Professor of Craniofacial
Biology, Center for Craniofacial Molecular Biology, Herman Ostrow School of
Dentistry, University of Southern California, Los Angeles, California
Fa-MingChen,Ph.D.,D.D.S.,ProfessorandDentalSurgeon,DepartmentofPeriodon-
tologyandOralMedicine,andTranslationalResearchTeam,SchoolofStomatology,
Fourth Military Medical University, Shaanxi, China
Mo Chen, Ph.D., Associate Research Scientist, Center for Craniofacial Regeneration,
Columbia University Medical Center, New York, New York
YiPing Chen, Ph.D., Professor, Department of Cell and Molecular Biology, Tulane
University, New Orleans, Louisiana
Choko Cho, Ph.D., Postdoctoral Fellow, Center for Craniofacial Regeneration,
Columbia University Medical Center, New York, New York
Michael T. Chung, B.S., Hagey Laboratory for Pediatric Regenerative Medicine,
Department of Surgery, Plastic and Reconstructive Surgery Division, Stanford
University School of Medicine, Stanford, California
Gang Ding, D.D.S., Ph.D., Associate Professor, Molecular Laboratory for Gene
Therapy and Tooth Regeneration, Capital Medical University School of
Stomatology, Beijing, China
ix
x CONTRIBUTORS
Mildred C. Embree, D.M.D., Ph.D., Assistant Professor, Center for Craniofacial
Regeneration, Columbia University Medical Center, New York, New York
Jifan Feng, Ph.D., Craniofacial Development and Stem Cell Biology, Biomedical
Research Centre, and MRC Centre for Transplantation, Dental Institute, King’s
College, London, UK; Postdoctoral Research Associate, Center for Craniofacial
Molecular Biology Herman Ostrow School of Dentistry, University of Southern
California, Los Angeles, California
Brian L. Foster, Ph.D., National Institute of Arthritis and Musculoskeletal and Skin
Diseases, National Institutes of Health, Bethesda, Maryland
JonathanA.Garlick,D.D.S.,Ph.D.,Professor,DivisionofCancerBiologyandTissue
Engineering, Department of Oral and Maxillofacial Pathology, School of Dental
Medicine, Tufts University, Boston, Massachusetts
Jeffrey Gimble, M.D., Ph.D., Professor, Stem Cell Biology Laboratory,
Pennington Biomedical Research Center, Louisiana State University System, Baton
Rouge, Louisiana
RolandoGittens,WallaceH.CoulterDepartmentofBiomedicalEngineering,Georgia
Institute of Technology, Atlanta, Georgia
SanderGrefte,Ph.D.,PostdoctoralResearcher,DepartmentofBiochemistry,Radboud
University Nijmegen Medical Centre, Nijmegen, The Netherlands
Stan Gronthos, Ph.D., Professor, Mesenchymal Stem Cell Laboratory, Department of
Haematology, University of Adelaide, Adelaide, South Australia, Australia
Monica Grova, B.S., Hagey Laboratory for Pediatric Regenerative Medicine,
Department of Surgery, Plastic and Reconstructive Surgery Division, Stanford
University School of Medicine, Stanford, California
Shuping Gu, D.D.S., Ph.D., Assistant Research Professor, Department of Cell and
Molecular Biology, Tulane University, New Orleans, Louisiana
Christopher D. Hermann, Ph.D., Wallace H. Coulter Department of Biomedical
Engineering, Georgia Institute of Technology, Atlanta, Georgia
Kyle J. Hewitt, Ph.D., Program in Cell, Molecular and Developmental Biology,
Sackler School of Graduate Biomedical Sciences, Tufts University, Boston,
Massachusetts
Joshua W. K. Ho, Ph.D., Instructor, Division of Genetics, Department of Medicine,
Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
Matthew P. Hoffman, B.D.S., Ph.D., National Institute of Dental and Craniofacial
Research, National Institutes of Health, Bethesda, Maryland
George T.-J. Huang, D.D.S., M.S.D., D.Sc., Professor, Director for Stem Cells and
Regenerative Therapies, Department of Bioscience Research, College of Dentistry,
The University of Tennessee Health Science Center, Memphis, Tennessee
Jeong S. Hyun, M.D., Postdoctoral Research Fellow, Hagey Laboratory for Pediatric
Regenerative Medicine, Department of Surgery, Plastic and Reconstructive Surgery
Division, Stanford University School of Medicine, Stanford, California
CONTRIBUTORS xi
John A. Jansen, D.D.S., Ph.D., Professor, Department of Biomaterials, Radboud
University Nijmegen Medical Centre, Nijmegen, The Netherlands
Andrew H. Jheon, D.D.S., Ph.D., Assistant Adjunct Professor, Department of
Orofacial Sciences and Program in Craniofacial and Mesenchymal Biology,
University of California–San Francisco, San Francisco, California
Nan Jiang, D.D.S., Center for Craniofacial Regeneration, Columbia University
Medical Center, New York, New York
Yan Jin, Ph.D., D.D.S., Professor, Research and Development Center for Tissue
Engineering, Fourth Military Medical University, Shaanxi, China
Maria Jussila, M.Sc., Developmental Biology Program, Institute of
Biotechnology, University of Helsinki, Helsinki, Finland
Emma Juuri, D.D.S., M.Sc. Developmental Biology Program, Institute of Biotech-
nology, University of Helsinki, Helsinki, Finland
L. Keller, INSERM UMR 1109, Team “Osteoarticular and Dental Regenerative
NanoMedicine,” Strasbourg, France; and Faculte´ de Chirurgie Dentaire, Universite´
de Strasbourg, Strasbourg, France
Robert G. Kelly, Ph.D., Investigator, Developmental Biology Institute of
Marseilles–Luminy, Aix–Marseille University, Marseille, France
OphirD. Klein,M.D.,Ph.D.,Associate Professor, Departments ofOrofacialSciences
andPediatrics,PrograminCraniofacialandMesenchymalBiology,andInstitutesfor
Human Genetics and Regeneration Medicine, University of California–San Fran-
cisco, San Francisco, California
KimiKong,Ph.D.,AssociateResearchScientist,CenterforCraniofacialRegeneration,
Columbia University Medical Center, New York, New York
S.Kuchler-Bopp,Ph.D.,Charge´ederecherche,INSERMUMR1109,Team“Osteoar-
ticularandDentalRegenerativeNanoMedicine,”Strasbourg,France;andFaculte´ de
Chirurgie Dentaire, Universite´ de Strasbourg, Strasbourg, France
Chang Hun Lee, Ph.D., Associate Research Scientist, Center for Craniofacial
Regeneration, Columbia University Medical Center, New York, New York
Christopher S. D. Lee, Ph.D., Wallace H. Coulter Department of Biomedical
Engineering, Georgia Institute of Technology, Atlanta, Georgia
Herve´ Lesot, Ph.D., Investigator, INSERM UMR 1109, Team “Osteoarticular and
Dental Regenerative NanoMedicine,” Strasbourg, France; and Faculte´ de Chirurgie
Dentaire, Universite´ de Strasbourg, Strasbourg, France
Yi Liu, D.D.S., Ph.D., Associate Professor, Molecular Laboratory for Gene Therapy
andToothRegeneration,CapitalMedicalUniversitySchoolofStomatology,Beijing,
China
David D. Lo, M.D., Postdoctoral Research Fellow, Hagey Laboratory for Pediatric
Regenerative Medicine, Department of Surgery, Plastic and Reconstructive Surgery
Division, Stanford University School of Medicine, Stanford, California
xii CONTRIBUTORS
Isabelle M. A. Lombaert, Ph.D., National Institute of Dental and Craniofacial
Research, National Institutes of Health, Bethesda, Maryland
MichaelT.Longaker,M.D.,M.B.A.,DeaneP.andLouiseMitchellProfessor,Hagey
LaboratoryforPediatricRegenerativeMedicine,DepartmentofSurgery,Plasticand
ReconstructiveSurgeryDivision,StanfordUniversitySchoolofMedicine,Stanford,
California;andInstituteforStemCellBiologyandRegenerativeMedicine,Stanford
University, Stanford, California
Richard L. Maas, M.D., Ph.D., Professor, Division of Genetics, Department of
Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston,
Massachusetts
Jeremy J. Mao, D.D.S., Ph.D., Professor and Zegarelli Endowed Chair, Center
for Craniofacial Regeneration, Columbia University Medical Center, New York,
New York
Avital Mendelson, Ph.D., Postdoctoral Fellow, Center for Craniofacial Regeneration,
Columbia University Medical Center, New York, New York
FredericMichon,Ph.D.,AcademyFellow,InstituteofBiotechnology,Developmental
Biology Program, University of Helsinki, Helsinki, Finland
Daniel T. Montoro, B.S., Life Science Research Associate, Hagey Laboratory for
PediatricRegenerativeMedicine,DepartmentofSurgery,PlasticandReconstructive
Surgery Division, Stanford University School of Medicine, Stanford, California
ChristianMorsczeck,M.Sc.,Ph.D.,Privatelecturer,DepartmentofCranio-andMax-
illofacial Surgery, University Hospital Regensburg, Regensburg, Germany
Misako Nakashima, D.D.S., Ph.D., Investigator, Department of Dental Regenerative
Medicine, Center of Advanced Medicine for Dental and Oral Diseases, National
Center for Geriatrics and Gerontology, Research Institute, Obu, Aichi, Japan
Hemin Nie, Ph.D., Postdoctoral Fellow, Center for Craniofacial Regeneration,
Columbia University Medical Center, New York, New York
Francisco H. Nociti, Jr., D.D.S., Ph.D., National Institute of Arthritis and
Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda,
Maryland; State University of Campinas School of Dentistry, Piracicaba, Sa˜o
Paulo, Brazil
Daniel J. O’Connell, Ph.D., Postdoctoral Fellow, Division of Genetics, Department
of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston,
Massachusetts
Rene Olivares-Navarrete, D.D.S., Ph.D., Senior Research Scientist, Wallace
H. Coulter Department of Biomedical Engineering, Georgia Institute of
Technology, Atlanta, Georgia
Carolina Parada, D.M.D, Ph.D, Center for Craniofacial Molecular Biology, Her-
man Ostrow School of Dentistry, University of Southern California, Los Angeles,
California