Selenium in poultry nutrition and health

433 Pages·2018·9.814 MB·English

by  Surai, Peter F

Peter F. Surai
Selenium in
poultry nutrition
and health
Wageningen Academic
P u b l i s h e r s
Selenium in poultry nutrition and health

Selenium

in poultry nutrition
and health
Peter F. Surai
Wageningen Academic
P u b l i s h e r s
Buy a print copy of this book at:
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DOI: 10.3920/978-90-8686-865-0
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Dedication
To my wife Helen, my daughter Katie, my son Anton,
my grandsons Oscar, Arthur and Henry
and my granddaughter Aiste
who gave me inspiration for writing this book.

About the author
Dr. Peter Surai started his studies at Kharkov
University, Ukraine, where he obtained his
PhD and DSc in biochemistry studying
effects of antioxidants on poultry. Later he
became Professor of Human Physiology. In
1994 he moved to Scotland to continue his
antioxidant related research in poultry and
in 2000 he was promoted to a full Professor
of Nutritional Biochemistry at the Scottish
Agricultural College. Recently he was
awarded Honorary Professorships in 5
universities in various countries, including
UK, Hungary, Bulgaria and Ukraine. In 2010 he was elected to the Russian Academy of
Sciences as a foreign member. He has more than 750 research publications, including
150 papers in peer-reviewed journals and 13 books. In 1999 he received the prestigious
John Logie Baird Award for Innovation for the development of ‘super-eggs’ and, in
2000, The World’s Poultry Science Association Award for Research in recognition of
an outstanding contribution to the development of the poultry industry. In 2017 he
became a member of the team at the Moscow State Academy of Veterinary Medicine
and Biotechnology named after K.I. Skryabin to conduct a research under a mega-
grant of the Government of Russian Federation (Contract No. 14.W03.31.0013).
For the last 15 years he has been lecturing all over the world visiting more than 70
countries.
Selenium in poultry nutrition and health 7

Table of contents
About the author 7
Preface 13
Abbreviations 15
Chapter 1
Antioxidant systems in animal body 19
1.1 Introduction 19
1.2 Free radicals and reactive oxygen and nitrogen species 19
1.3 Three levels of antioxidant defence 23
1.4 Superoxide dismutase in biological systems 26
1.5 Superoxide dismutase in avian biology 29
1.6 Other antioxidant mechanisms 30
1.7 Oxidative stress and transcription factors 46
1.8 Vitagene concept development 50
1.9 Conclusions 53
References 54
Chapter 2
Molecular mechanisms of selenium action: selenoproteins 67
2.1 Introduction 67
2.2 The selenoprotein family 67
2.3 Selenocysteine: the functional selenium 68
2.4 Glutathione peroxidases 70
2.5 Glutathione peroxidase activity effectors 83
2.6 GSH-Px and their biological roles 91
2.7 Thioredoxin reductases as a major part of the thioredoxin system 93
2.8 Iodothyronine deiodinases 99
2.9 Other selenoproteins 103
2.10 General conclusions 119
References 122
Chapter 3
Selenium in feed: organic selenium concept 153
3.1 Introduction 153
3.2 Selenium in soils and plants 153
3.3 Selenium absorption and metabolism 160
3.4 Selenium status and bioavailability 169
3.5 Effectors of selenium absorption, metabolism and bioavailability 171
3.6 Selenium sources for poultry 172
3.7 Selenium-enriched yeast: pluses and minuses 175
3.8 SeMet and OH-SeMet 178
Selenium in poultry nutrition and health 9