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About Rossi Review
This document discusses RNA interference (RNAi) as the basis for new therapeutic approaches and reviews the current state of RNAi-based drugs. Several companies have RNAi drugs in clinical trials that target genes involved in eye diseases, viral infections, and genetic skin disorders. The document outlines the mechanisms of RNAi and challenges for therapeutic application, particularly delivery of siRNAs to target cells. Effective delivery strategies discussed include nanoparticles, cationic lipids, viral vectors, and conjugating siRNAs to ligands like cholesterol to target specific tissues.
Detailed Information
| Author: | ['unicycle1234'] |
|---|---|
| Publication Year: | 2013 |
| Pages: | 10 |
| Language: | English |
| Format: | |
| Price: | FREE |
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