Proteins, Peptides and Amino Acids SourceBook

1071 Pages·2002·162.56 MB·English

by  John Stephen White

PROTEINS, PEPTIDES AND AMINO ACIDS
SOURCEBoOK
PROTEINS, PEPTIDES AND
AMINO ACIDS
SOURCEBoOK
JOHN STEPHEN WHITE
DOROTHY CHONG WHITE
WHITE Technical Research GROUP, Argenta, IL
~
~
SPRINGER-SCIENCE+BUSINESS MEDIA, LLC
© 2002 Springer Science+Business Media New York
Originally published by Humana Press !ne. in 2002
Softcover reprint of the hardcover 1s t edition 2002
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Library of Congress Cataloging-in-Publication Data
White, John Stephen, 1958-
Proteins, peptides and amino acid sourcebook 1 John Stephen White, Dorothy Chong White.
p. cm.
Includes index.
ISBN 978-1-4684-9679-6 ISBN 978-1-59259-170-1 (eBook)
DOI 10.1007/978-1-59259-170-1
1. Proteins-Handbooks, manuals, etc. 2. Peptides-Handbooks, manuals, etc. 3. Amino acids-Handbooks, manuals, etc. 4. Proteins
Directories. 5. Peptides-Directories. 6. Amino acids-Directories. 1. White, Dorothy Chong. II. Title.
QP55l.W53 2002
572'.6-dc21
2002022200
It is to our children-
Paul, Elise, Diana, Jessamyn, and Samuel
-that we dedicate this book.
Their understanding and encouragement were given without reservation
throughout a process that lasted longer than any of us bargained for.
PREFACE
Proteins, Pep tides and Amino Acids SourceBook is the second in a series of reference
books conceived to cover the explosive growth in commercially available biological
reagents. The success of our first reference work, Source Book of Enzymes published in
1997, encouraged us to continue this series. Choosing proteins, peptides, and amino
acids as the subject matter for the second volume was simple, given their preeminence
in regulating biochemical processes and their importance to modern molecular biology.
The SourceBook series was inspired by our difficulty in locating a suitable replacement
for a depleted reagent in the midst of an urgent research project. To our dismay, we
found the reagent supplier out of business and the product line no longer available.
Other reagent catalogs on our library bookshelf offered a narrow selection and incom
plete functional information. We were ultimately able to locate a satisfactory alternative
only by making countless inquiries and paging through innumerable product catalogs
and technical data sheets. We needed-but could not find-a single resource that
cataloged available compounds, organized them in a logical and accessible format,
provided critical technical information to distinguish one from another, and told us
where we could buy them.
We conceived the SourceBook series as a unique reference tool to satisfy this need. It
has been carefully designed to inform users of the broad variety of reagent products
available from commercial suppliers worldwide. Proteins, Peptides and Amino Acids
SourceBook facilitates the selection process by providing systematic and comparative
functional information about each product. The task of maintaining and searching
scores of supplier catalogs and product data bulletins is eliminated.
Proteins, Pep tides and Amino Acids SourceBook will be a practical tool for researchers in
academia, industry, and government. Students and educators will regularly refer to its
concise information and helpful indexes. Reagent suppliers and marketers will find the
SourceBook an invaluable resource in conducting competitive assessments and identify
ing new product trends and opportunities. And to speed their identification and order
ing of specific products, purchasing agents will rely on Proteins, Peptides and Amino Acids
SourceBook's distillation of critical product information into thorough reference tables
and a comprehensive index of worldwide suppliers, brokers and distributors.
Proteins, Peptides and Amino Acids SourceBook is organized in a user-friendly format
that combines the following unique features in one expansive volume:
• An encyclopedic comparison of more than 26,000 commercially available proteins,
peptides, and amino acids.
• A worldwide listing of nearly 500 reagent suppliers, brokers and distributors.
• Critical functional information, proven applications and literature references.
• Comparative sequence, biological source, molecular weight, purity, biochemical and
physical data, and physical form information to ensure the selection of suitable products.
Vll
viii Preface
• An informative User's Guide that takes the reader through the unique features of Proteins,
Pep tides and Amino Acids SourceBook.
• Helpful listing of abbreviations and acronyms used throughout the world in describing
proteins, pep tides and amino acids.
• Complete indexes of peptide sequences and names, synonyms and derivatives.
It is our hope that Proteins, Pep tides and Amino Acids SourceBook finds a place on your
bookshelf as a valued research tool, and that it eases the process of locating the reagent and
supplier best suited to your needs and geographic location.
We made a concerted effort to make Proteins, Pep tides and Amino Acids SourceBook an
exhaustive and global compendium of all commercially available proteins, peptides and
amino acids. That we fell short of this goal is due in part to our ignorance of additional
suppliers and our inability to keep pace with the development and commercialization of
new products. If we overlooked your products, please accept our apology and invitation to
contribute to the next edition.
Because of the continuing discovery, development, and commercialization of new reagents
and sources, the information in this book will quite naturally become dated. To address this
shortcoming, the authors and publishers are committed to updating Proteins, Pep tides and
Amino Acids SourceBook and the SourceBook series on a regular basis. We welcome your
suggestions for corrections and additions to the books. Particularly valued are your
suggestions for improving the content, readability, accessibility and organization.
John Stephen White
Dorothy Chong White
WHITE Technical Research GROUP
8895 Hickory Hills Drive
Argenta, Illinois 62501 USA
Phone: [phone]
E-mail: [email protected]
About the Authors
Dorothy Chong White has worked for twenty years in the corn wet-milling industry,
holding varied positions in basic research and product development for the A.E. Staley
Manufacturing Company in Decatur, Illinois (a subsidiary of Tate & Lyle, North America).
She has developed considerable expertise in manufacturing process troubleshooting and
product characterization. She has the distinction of being a member of the research team
which won technical approval for 100% use of high fructose corn syrup-55 as a replacement
for sucrose in the carbonated beverage industry.
Ms. White holds two US patents and has been actively engaged in new product
development from biotechnology for the past five years. Her scientific training was taken
at the Universities of Illinois at Champaign-Urbana and Springfield.
John Stephen White developed an enduring fascination for the use of enzymes and other
biological reagents through practical experience in the isolation and purification of enzymes
Preface ix
for academic research, development of a multi enzyme in vitro enzyme system to predict the
in vivo digestibility of carbohydrate polymers, and large-scale applications of enzymes for
food and industrial ingredient manufacture.
His training in biochemistry was taken at the University of California at San Diego and the
University of Utah, Salt Lake City. Dr. White held joint appointments at the University of
Illinois, Champaign-Urbana, as postdoctoral fellow and visiting assistant professor of
biochemistry. He spent thirteen years in research and management in the corn wet-milling
industry, one of the largest consumers of commercial bioreagents, and is the author of more
than 25 journal articles, book chapters and reference books.
Dr. White has worked extensively with scientists from the food and beverage industries,
academia and government to investigate nutritional issues surrounding traditional and
novel foods and ingredients. He has enjoyed professional affiliations with the Calorie Control
Council, the Corn Refiners Association, the Institute of Food Technologists, and the
International Life Sciences Institute, which he has served as trustee and scientific advisor.
Dr. White is founder and principal in the consulting firm of WHITE Technical Research
GROUP, established in 1994 to serve scientific research and management.
Acknowledgments
The authors express their gratitude to the many marketing, technical service, customer
service, research, and public affairs personnel from reagent suppliers who gave so generously
oftheir time to provide us with technical information about their protein, peptide and amino
acid products.
Finally, we thank our long-suffering editors and publishers at Humana Press for their
support, encouragement and prodding during development of this book. We hope you
agree that it was worth the wait.
CONTENTS
Preface ............................................................................................. vii
PART 1 User's Guide ......................................................................... 1
PART 2 Proteins ................................................................................. 5
PART 3 Peptides-Sequences and Modifications ......................... 207
PART 4 Peptides-Sequences Not Specified ................................ 671
PART 5 Amino Acids and Derivatives ........................................... 715
PART 6 Appendices
Appendix A. Reagent Suppliers ....................................... 941
Appendix B. Glossary of Abbreviations
and Acronyms .............................................................. 963
PART 7 Indexes
Index A. Peptide Sequences ............................................. 975
Index B. General Index-Compound Names,
Synonyms, and Derivatives ....................................... 1021
xi
User's Guide
Part 1. User's Guide
White & White - Proteins, Peptides & Amino Acids SourceBook 1
User's Guide
Like other volumes in this series, Proteins, Peptides & Selecting the right product for your
Amino Acids SourceBook was created with two primary application. ..
purposes in mind: to increase accessibility to globally
available products and provide technical information to aid
is the final step once the compound is located. Proteins,
the product selection process. In Part 1, we will guide you
Peptides & Amino Acids SourceBook simplifies this task by
through the product selection process using information
providing product-specific technical data in an easy-to-use
found in Proteins, Pep tides & Amino Acids SourceBook.
format that encourages product comparisons.
If you know the protein or amino acid
Use the technical data as selection criteria for comparing
name. .. and contrasting available products from different suppliers.
Select that product which most nearly matches your
locating the compound is easy, since information in requirements for sequence, sequence modification,
Proteins, Peptides & Amino Acids SourceBook is grouped chemical derivative, preparation form, purity, composition,
alphabetically within these natural categories. Proteins are activity, functionality and temperature/pH optima.
listed in Part 2, beginning on page 5. Amino acids and • Biological source-responsible for the wondrous
their derivatives are listed in Part 5, beginning on page variety in sequence, stability, reactivity,
715. temperature and pH optima, molecular weight and
activity.
If you cannot readily locate a protein or • Molecular weight-given in units of molar mass for
amino acid. .. small molecules or Daltons for macromolecules.
• Preparation form-describes the physical form of
the product (crystallized, lyophilized, etc.) and
consult the General Index, beginning on page 1021.
any added buffers, salts, stabilizers or
Compounds and page locations are listed alphabetically
preservatives. Discloses product contaminants.
within this index by name, synonym and derivative
• Product notes-lists compound importance, known
formula.
applications and literature references.
If you are looking for a specific peptide. ..
Confused about. ..
the compound will be located in either of two sections,
a term or abbreviation used in the product data tables?
depending on whether sequence information was provided
Appendix B, beginning on page 963, contains an extensive
by the supplier. Peptides with known sequences are listed
Glossary of terms used in Proteins, Pep tides & Amino Acids
alphabetically by basiC sequence (no modification) in Part
SourceBook that will clarify those with which you are
3, beginning on page 207. Peptides lacking supplier
unfamiliar.
sequence information are listed alphabetically by name in
Part 4, beginning on page 671.
To order the selected product. ..
If you cannot readily locate a peptide. ..
simply record the supplier'S catalog number from the
product listing and locate their office, broker or distributor
consult the Sequences Index, beginning on page 975.
closest to you from the Reagent Supplier Appendix
Basic peptide sequences, without chemical modifications,
(Appendix A), beginning on page 941.
are arranged alphabetically within this index. If you still
cannot locate the product, consult the General Index,
Conventions. ..
beginning on page 1021. It may be that the compound
you seek is a fragment of a larger protein, or that the
name you seek is a synonym for a compound with a more Verbal descriptions of product attributes have been
common name. Compounds and page locations are listed condensed and standardized in order to simplify reader
alphabetically in this index by name, synonym and comparisons. The authors have endeavored to do this
derivative formula. without compromising supplier product claims.
If you only know the acronym. .. The abbreviations and acronyms used in this work are
those in common use; they are listed in Appendix B of Part
6. Since they differ somewhat around the world, we
consult the Glossary of Abbreviations & Acronyms
adopted for use those that seemed most descriptive and
(Appendix B), beginning on page 963. The product you
straightforward. New abbreviations and acronyms were
seek likely appears in Proteins, Pep tides & Amino Acids
coined only where necessary to avoid ambiguity.
SourceBook under its full name.
The authors have made every attempt to ensure that the
Browsing can be beneficial. ..
information contained in this work is accurate. Since the
field of proteins, peptides and amino acids is changing so
even if you don't have a specific purpose in mind. You
rapidly, readers are encouraged to verify product
may browse the General and Sequences Indexes for
information with suppliers before ordering.
names, synonyms, derivative formulas or basic sequences
that complement your application. Alternatively, novel
Information for this book was gathered from supplier
applications may occur to you while browsing information
catalogs, data sheets and electroniC data bases. Obvious
within the broad protein, peptide or amino acid sections of
discrepancies between suppliers were resolved where
Parts 2-5.
possible. The sheer volume of data in this work, however,
made it impossible to verify the veraCity of each supplier's
claims.
2 User's Guide pp. 1-2, Glossary/Indexes pp. 963-1063