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Models of viral hepatitis PDF

173 Pages·2005·1.177 MB·English
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by Fritz von Weizsäcker, Michael Roggendorf| 2005| 173 pages| 1.177| English

About Models of viral hepatitis

Viral hepatitis B or C is the most common cause of chronic liver disease worldwide and accounts for about 80% of all hepatocellular carcinoma cases. Thus, combating viral hepatitis remains one of the most pressing public health issues today. Animal models and cell-based systems are essential tools for addressing the many still unresolved basic and clinical problems. Experimental models are needed to better understand the viral life cycles, pathogenetic aspects and natural defense mechanisms, while preclinical models are required for evaluating novel preemptive and therapeutic strategies. This monograph provides a unique synopsis of currently available models of viral hepatitis, highlighting their particular use for basic and translational science. Leading experts discuss new scientific results and evolving methods in various animal and in vitro models, including the woodchuck, duck, mouse, chimpanzee and tupaia, as well as primary hepatocytes and subgenomic HCV replicons.A valuable

Detailed Information

Author:Fritz von Weizsäcker, Michael Roggendorf
Publication Year:2005
ISBN:9783805578097
Pages:173
Language:English
File Size:1.177
Format:PDF
Price:FREE
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