Lung transplantation : principles and practice

442 Pages·2015·92.267 MB·English

by  Garrity, Edward R., Odell, John A., Vigneswaran, Wickii T

SURGERY
Vigneswaran
Garrity
LUNG Odell

Transplantation
Principles and Practice
LUNG
Lung Transplantation: Principles and
Practice covers the current practice in donor
and recipient management as well as current
treatment strategies and outcomes.
With 39 chapters from international experts
in the field, the book is divided into four broad
sections: General Topics, Donor Management,
Recipient Management and Outcome, and the Transplantation
Future of Lung Transplantation.
The book discusses significant advances
achieved in the past decade in areas such
as donor allocation, organ preservation and Principles and Practice
management, recipient selection, management
and support, surgical and critical care
techniques, immune suppression, and infection
prophylaxis. Specific instances of pulmonary
disease that commonly necessitate lung
transplantation are also covered.
Generously illustrated in full color, this valuable
resource is relevant to both specialists and
Edited by
other providers who may refer or care for
patients before and after transplantation. Wickii T. Vigneswaran
Edward R. Garrity, Jr.
John A. Odell
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K22975 EBOOK
ISBN: 978-1-4822-3391-9
90000
9 781482 233919

Dedication
To all my mentors and teachers for their patience, to my patients whom I had the privilege to serve, and to my wife Rupy and
children Yalini, Hari and Janani for their support and the sacrifices they have made.
WTV
To all the patients who have been the real pioneers in this field—thank you for your trust and support of our endeavors.
Breathing is good!
And to my wife Linda, who has helped to keep me level and patient-centered throughout.
ERG
To my patients, who had the courage and confidence to accept me as their surgeon and to place their lives in my hands. I would
also like to dedicate this to the donors and their families, who have made the lives of others better.
JAO

Contents
Preface ix
Acknowledgments xi
Contributors xiii
PArt 1 GENErAL tOPICS
1 History of lung transplantation 3
Joel D. Cooper and Thomas M. Egan
2 Immunology of lung transplantation 13
Adam S.A. Gracon and David S. Wilkes
3 Ethical considerations in transplantation: A focus on lung transplantation 23
Baddr A. Shakhsheer, Sean C. Wightman, Savitri Fedson, and Mark Siegler
4 Indications for lung transplantation and patient selection 29
Joshua S. Mason, Julia B. Becker, and Edward R. Garrity Jr.
5 Recipient management before transplantation 55
Gundeep S. Dhillon and David Weill
PArt 2 DONOr MANAGEMENt
6 Allocation of donor lungs 67
Mark J. Russo
7 Donor selection and management 75
Joseph Costa, Frank D’Ovidio, and Joshua R. Sonett
8 Non–heart-beating donors 89
David Gómez de Antonio, Jose Luis Campo Cañaveral de la Cruz, Lucas Hoyos Megía,
Daniel Valdivia Concha, and Andrés Varela de Ugarte
9 Donor lung preservation 97
Wiebke Sommer and Gregor Warnecke
10 Donor procurement 105
Hassan Michael Nemeh and Natalie Madoun
11 Ex vivo lung perfusion 111
Thorsten Krueger, Marcelo Cypel, and Shaf Keshavjee
PArt 3 rECIPIENt MANAGEMENt AND OUtCOME
12 The humoral response to lung transplantation 121
Glen P. Westall, Miranda A. Paraskeva, and Greg I. Snell
13 Anesthesia for lung transplantation 133
J. Devin Roberts, Mohammed Minhaj, and Mark A. Chaney
14 Mechanical ventilation and extracorporeal membrane oxygenation (ECMO):
Bridges to lung transplantation 139
James J. Yun and David P. Mason
vii
viii Contents
15 Single-lung transplantation: Technical aspects 145
Christopher Wigfield and Wickii T. Vigneswaran
16 Bilateral sequential lung transplantation: Technical aspects 151
Mara B. Antonoff and G. Alexander Patterson
17 Heart-lung transplantation: Technical aspects 159
Matthias Loebe, Xiang Wei, and Dewei Ren
18 Lobar lung transplantation from living donors 165
Hiroshi Date
19 Technical aspects of redo lung transplantation and lung transplantation after previous thoracotomy 175
Shelly Bansal and John A. Odell
20 Lung transplantation for idiopathic pulmonary fibrosis 183
Joshua C. Grimm, Leann L. Silhan, and Ashish S. Shah
21 Lung transplantation for emphysema and α-antitrypsin deficiency 191
1
Walter Weder and Ilhan Inci
22 Lung transplantation for cystic fibrosis and bronchiectasis 203
John H. Dark
23 Lung transplantation for pulmonary hypertension 213
Stéphane Collaud and Marc de Perrot
24 Lung transplantation for connective tissue disorders 223
Abbas Ardehali
25 Posttransplantation critical care management 229
Cesar A. Keller and José L. Díaz-Gómez
26 Primary graft dysfunction 251
Catherine Borders, John Ellis, Edward M. Cantu III, and Jason D. Christie
27 Management of surgical complications 265
Mathew Thomas and John A. Odell
28 Immunosuppression strategies in lung transplantation 279
Miranda A. Paraskeva, Glen P. Westall, and Greg I. Snell
29 Viral infections in lung transplantation 293
Lara Danziger-Isakov, Erik Verschuuren, and Oriol Manuel
30 Fungal infections in lung transplantation 307
Melissa Gitman and Me-Linh Luong
31 Bacterial infections after lung transplantation 321
Jennifer Delacruz, Jennifer L. Steinbeck, Kenneth Pursell, and David Pitrak
32 Diagnosis of lung rejection and infection: A pathologist’s perspective 335
Vijayalakshmi Ananthanarayanan and Aliya N. Husain
33 Obliterative bronchiolitis/bronchiolitis obliterans syndrome: Etiology, diagnosis, and management 345
Susan R. Russell and Sangeeta M. Bhorade
34 Chronic lung allograft dysfunction other than bronchiolitis obliterans syndrome 359
Stijn E. Verleden, Robin Vos, Bart M. Vanaudenaerde, and Geert M. Verleden
35 Medical complications of lung transplantation 371
Keith C. Meyer
36 Malignancy following lung transplantation 385
Katherine M. Vandervest and Martin R. Zamora
37 Quality of life following lung transplantation 395
Nathan M. Mollberg and Michael S. Mulligan
PArt 4 FUtUrE OF LUNG trANSPLANtAtION
38 Future therapies in lung transplantation 403
Elizabeth A. Lendermon and John F. McDyer
39 New horizons in lung transplantation 413
Jason M. Long and Wickii T. Vigneswaran