Table Of ContentEssentials in Ophthalmology
Series Editor: Arun D. Singh
Jorge L. Alió
Jorge L. Alió del Barrio Editors
Atlas of Anterior
Segment Optical
Coherence
Tomography
Essentials in Ophthalmology
Series Editor
Arun D. Singh
More information about this series at http://www.springer.com/series/5332
Jorge L. Alió • Jorge L. Alió del Barrio
Editors
Atlas of Anterior
Segment Optical
Coherence Tomography
Editors
Jorge L. Alió Jorge L. Alió del Barrio
Vissum Alicante University Vissum-Instituto Oftalmologico de Alica
Alicante Miguel Hernandez University
Spain Alicante
Spain
ISSN 1612-3212 ISSN 2196-890X (electronic)
Essentials in Ophthalmology
ISBN 978-3-030-53373-1 ISBN 978-3-030-53374-8 (eBook)
https://doi.org/10.1007/978-3-030-53374-8
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Preface
This book deals with one of the latest and most important developments in
diagnostic imaging in ophthalmology – Optical coherence tomography
(OCT) and its applications to the study of the anterior segment of the eye.
Since its early development, when this technology was basically applied
to study the posterior segment of the eye and particularly the macula, OCT
has become an essential tool in the practice of ophthalmology. Nowadays, its
application, aided by innovations in implementation, has allowed the study of
the cornea, lens, and, in general, the anterior segment, including the ocular
surface and glaucoma, and is now an essential element in the diagnosis and
treatment guidance of anterior segment diseases.
Until recently, we had very few tools for the anterior segment of the eye
other than biomicroscopy, gonioscopy, and anterior segment photography.
Confocal microscopy was one of the innovations, but it never gained popular-
ity in general clinical application, in spite of its scientific usefulness, owing
to the small area from which it offers information (the central cornea, essen-
tially), its relative complexity, the need for a skillful observer, frequently dif-
ficult interpretation, and the need for a cooperative patient. Anterior segment
OCT (AS-OCT) has, on the contrary, overcome these disadvantages, and any
technician or non-expert ophthalmologist can use it easily with basic training.
Also, anterior segment OCT requires minimal cooperation from the patient;
it is fast, non-invasive, and comfortable for general application in the often
busy anterior segment clinic.
The sharp imaging that current anterior segment OCT devices provide, has
make this technology to become a tool that goes beyond the limits of pure
diagnostic imaging and provides in-depth anterior segment diagnosis.
This book is aimed at those who are introducing or are already using
AS-OCT in their clinical practice. It is to be considered, as a text and atlas, a
didactical tool using a systematic approach for the description and resolution
of problems similar to Hippocratic teaching.
At the time of Hippocrates, when classical medicine was practiced in
ancient Greece in the temples devoted to Aesculapius, pupils were guided in
their education by the master and lessons were taught by observing and
examining patients. This is exactly one of the methods we use here, taking the
reader through different cases that show a wide range of examples of the
applications of AS-OCT for diagnosis and the keys to its correct use and
interpretation as well as therapeutic resolution of difficult, rare, or complex
vii
viii Preface
cases. In addition, the reader will find chapters that go in depth into the fun-
damentals and applications of this diagnostic technique. The chapter on
future perspectives speculates about the development of this technology in
the next 10 to 15 years.
I hope the readers will be introduced to and educated in the proper use of
AS-OCT. I do think that all practicing clinicians will find the case reports that
we have included here very interesting and informative.
I also want to thank the authors who have contributed their knowledge and
expertise and donated their time to this essay in medical education.
Alicante, Spain Jorge L. Alió
Jorge L. Alió del Barrio
Contents
1 Anterior Segment OCT: An Overview . . . . . . . . . . . . . . . . . . . . . 1
Shinichi Fukuda, Yoshiaki Yasuno, and Tetsuro Oshika
2 Anterior Segment OCT: Fundamentals and
Technological Basis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
Gabriele Vestri, Claudio Macaluso, and Francesco Versaci
3 Anterior Segment OCT: How to Choose for Your Practice . . . . 21
Miguel J. Maldonado, Melissa G. Paragua Macuri, and
Alfredo Holgueras
4 Anterior Segment OCT: Clinical Applications . . . . . . . . . . . . . . . 31
Ahmed A. Abdelghany, Jorge L. Alió,
Jorge L. Alió del Barrio, Laura Primavera, Francesco D’Oria,
Chiara Fariselli, Amar Agarwal, Anthony J. Aldave,
Beatriz Castaño Martin, Dan Z. Reinstein,
Dhivya Ashok Kumar, Duangratn Niruthisard, Eitan Livny,
Francisco Arnalich Montiel, Giovanni Alessio, Irit Bahar,
Maria Alejandra Amesty, Miguel A. Teus, Ryan S. Vida,
Timothy J. Archer, Uri Elbaz, Yariv Keshet, and Yoav Nahum
5 Anterior Segment OCT: Angiography . . . . . . . . . . . . . . . . . . . . . 159
Marcus Ang, Darren S. J. Ting, Chelvin C. A. Sng, and
Leopold Schmetterer
6 Anterior Segment OCT: High- Resolution Tomography of
Corneal and Conjunctival Lesions . . . . . . . . . . . . . . . . . . . . . . . . 171
Sarah Wall, Despoina Theotoka, Asaf Friehmann, and Carol
L. Karp
7 Anterior Segment OCT: Real-Time Intraoperative OCT
in Corneal Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181
Moushmi Patil, Marcus Ang, and Jodhbir S. Mehta
8 Anterior Segment OCT: Real-Time Intraoperative OCT
in Cataract Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191
Boris Malyugin and Natalia Anisimova
9 Anterior Segment OCT: Observations in Corneal
Stroma Regeneration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207
Jorge L. Alió del Barrio, Mona El Zarif, and Jorge L. Alió
ix
x Contents
10 Anterior Segment OCT: Application in Stromal
Lenticule Addition Keratoplasty (SLAK) . . . . . . . . . . . . . . . . . . . 211
Leonardo Mastropasqua, Mario Nubile, Niccolò Salgari,
Jessica Bondì, Emanuele Erroi, and Luca Cerino
11 Anterior Segment OCT: Application to Improve Graft
Selection for Corneal Transplantation . . . . . . . . . . . . . . . . . . . . . 223
Berthold Seitz, Fatema Asi, Stephanie Mäurer, Loic Hamon,
Adrien Quintin, and Achim Langenbucher
12 Anterior Segment OCT: Polarization-Sensitive OCT . . . . . . . . . 237
Shinichi Fukuda, Yoshiaki Yasuno, and Tetsuro Oshika
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251
