Table Of ContentAUTHOR  INDEX  5 
Bold type indicates authors of commentaries, editorials, letters, and Resource Corners; (No.) indicates issue number. 
Abbruzzese JL, 2  Crowther M, 29  Havranek EP, 80 
Adhikari N, 58  Cunningham D, 2  Haydel MJ, 42 
Allenberg J, 33  Curhan GC, 22  Haynes B, 53 
Allum WH, 2  Curtis SP, 44  Hayward AC, 61 
Andersohn F, 75  Cutler JA, 16  Heart Protection Study Collaborative 
Antonini A, 76  Cuzick J, 4  Group, 50 
Appleton S, 18  Dagerman KS, 35  Henehan C, A-8—A-9 (No. 2) 
Aschner P, 39  Darmon M, 69  Henry D, 24 
Baerlocher MO, 23  Davis BR, 16  Herrera S, 51 
Bagnardi V, 48  Day A, 62  Heyland D, 62 
Baillie C, 64  De Lena M, 31  Hilden J, A-12 (No. 3) 
Balk E, 59  de Morton N, 72  Hillegass WB, 49 
Bandeira-Echtler E, 40  De Seigneux S, 14  Hillner BE, 4 
Baron MA, 74  Dejager S, 74  Hirsch C, 34 
Barter P, 30  Denman M, 44  Hlatky MA, 49 
Bartle B, 77  Detar DT, 23  Ho PM, 47 
Bates ER, 66—67  Detsky ME, 23  Hollingsworth JM, 22 
Bax JJ, 20  Di Castelnuovo A, 48  Holroyd-Leduc J, 42 
Bergerhoff K, 40  Dickersin K, A-8—A-9 (No. 1), A-11 (No. 2)  Howard PA, 52 
Beswick A, 80  Ding EL, 25  Howell A, 4 
Beyssen B, 32  Dodek P, 62  Hylek E, 52 
Bijker N, 3  Douillard JY, 31  Ilanne-Parikka P, 37 
Bingisser R, 57  DouketisJ , 46  Isley WL, 10-11 
Biondi-Zoccai GG, 58  Duffy M, 43 
Jefts K, 72 
Black DM, 64  Dunn A, 51  John O, 45 
Blanc JJ, 41  Durga J, 71  Johnson BE, 65 
Bogaisky M, 71  Ebrahim SH, 40, 80  Johnston SC, 79 
Bohlius J, 6  Edmonds M, 21  Jones D, 5 
Bosch J, 10  Edwards K, 11  Julian JA, 1 
Bosch J, 8  Elliott WJ, 73  Juurlink D, 12 
Bradley CP, 24  Ellis PM, 31  Kaatz S, 46 
Briel M, 66  Ensrud KE, 64  Kashani A, 70 
Brindle P, 80  Evans AT, 41  Katon WJ, 78 
Bronson DL, 70  Evans CA, 45  Kaufman SR, 22 
Brott BC, 49  Fahey T, 80  Kearon C, 1 
Bruckmann H, 33  Fihn SD, 47  Keating J, 72 
Brun-Buisson C, 62  Finckh A, 43  Khatcheressian J, 5 
Brunner-La Rocca HP. 67  FitzGerald GA, 44  Kipnes MS, 39 
Bryson CL, 47, 50  Foody JM, 70  Klarenbach S, 14 
Bucher HC, 66  Frasure-Smith N, 68  Koszycki D, 68 
Buckley NS, 17  Friedrich J, 58  aCroix  AZ, 65 
Buckley NS, 19  Gandhi GY, 8, 10-11  aine L, 13 
Buser PT, 67  Garbe E, 75  andoni G, 58 
Buzdar A, 4  Garcia D, 52  aRosa Ke s 30 
Camus C, 15  Gatto G, 76  arson E, 35 
Cannon CP, 44  Gerstein  HC, 8, 10  au J, 38 
Ceglia L, 38 
Ghersi D, 5  autrette A, 69 
Chan FKL, 13  Gill SS, 72  Lee S$, 53 
Chang S, 9  Gilman RH, 45  Lee TA, 77 
Chatellier G, 32  Ginsberg By]  Leeuw PW, 59 
Chen S, 53  Glasziou P, A-8—A-9, (No. 1), A-11  (No. 2)  Legnani C, 29 
Cheng E, 7  Goldman LE, 21  Leipzig RM, 71 
Chessman AW, 23  Gonzalez EB, 77  I esperance FE, 68 
Christ-Crain M, 57  Grab JD, 81  LeungJ , 43 
Chua BH, 3  Graff MJ, 34  Leung WY, 9 
Chung M, 59  Granger R, 36  Lin EH, 78 
Clar C, 40  Granwehr B, 60  Linden W, 68 
Combes A, 15  Gregor P, 12  Lindstrém J, 37 
Cook D, 62  Grifoni S, 46  Lunceford  JK, 39 
Cook D, 69  Guyatt G, A-8-A-9, (No. 1), A-11 (No. 2)  Magazzini S, 46 
Cosmi B, 29  Hankey GJ, 79  Mahnken  JD, 52 
Costanzo S, 48  Harling R, 61  Martin J, A-10 (No. 1) 
Craddock D, 11  Haverkamp W, 75  Mas Jl ’ 32 
MAY/JUNE 2007 |V OLUME  146 * NUMBER 3 
ACP JOURNAL CLUB
AUTHOR  INDEX 
Masoudi FA, 47  Quartieri F, 41  Spertus JA, 47 
Massel D, 75-76  Raman G, 59  Stein ND, A-8-A-9 (No. 1), A-11  (No. 2) 
McCall KL, 11  Ran ZH, 63  Stenning SP, 2 
McCurry S, 35  Ranji SR, 21  Stolz D, 57 
McDonald DR, 23  Reed SD, 65  Straus S, A-8—A-9 (No. 2), A-11 (No. 2), 42 
McGeer A, 36  Richter B, 40  Stroupe KT, 49 
McGettigan P, 24  Rifkin DE, 81  Suissa S, 75 
Megarbane B, 69  Ringleb PA, 33  Sullivan EF, 37 
Mehta RH, 81  Rocker G, 69  Suskin N, 75-76 
Meijnen P, 3  Rogers MA, 22  Swiglo BA, 8 
Meyer PM, 73  Rosell R, 31  Szmitko PE, 12 
Mills D, 74  Rosenstock J, 74  Tariot PN, 35 
Moayyedi P, 63  Rothwell PM, 79  Terespolsky D, 53 
Molony DA, 25  Rotthoff JR, 60  The SPARCL Investigators, 7 
Montori VM, 74  Roy A, 17  Thijssen M, 34 
Moore DA, 45  Rudd P, 16  Thorpe KE, 42 
Morrison DA, 49  Sackett DL, 32-33  Tonelli M, 15 
Muscedere J, 62  Sacks HS, 61  Tong  JL, 63 
Newton  KM, 65  Salpeter EEF, 17, 19  Trujillo-Santos J, 51 
Neuyen-Huynh MN, 79  Salpeter SR, 12, 17, 19  Tsuyuki RT, 9 
Niederberger M, 14  Sarnak MJ, 81  Tumlin JA, 58 
Niewoehner DE, 57  Saudan P, 14  van Boxtel MP. 71 
Nordmann AJ, 66  Schade R, 75  van  Dijk N, 41 
O’Brien SM, 81  Schneider  ANE 35  Vanni S, 46 
O’Malley PG, 30, 78  Schouten  EG, 71  Vernooij-Dassen MJ, 34 
Oczkowski W, 32-33  Schouten O, 20  Victor JC, 60 
Ohmit SE, 60  Schwartz AV, 64  Vinsonneau C, 15 
OrmistoTnM,  12, 17  Schweizer  A, 74  Walters +B 36 
Padwal R, 73  Scott IA, 20, A-8-A-11  (No. 3)  Wang W, 53 
Page MA, 51  Seidenfeld  J, 6  Waters DD, 30 
Palareti G, 29  Shafazand S, 18-19  Weiss KB, 77 
Pannu N, 14, 15  Shah NR,  A-11  (No.  1)  Welborn J, 6 
Peltonen M, 37  Shekelle P, 48  Werten S, 61 
Perera R, A-8—A-9 (No. 2)  Shen J, 63  White RH, 1 
Peterse JL, 3  Shireman TI, 52  Wilcken N, 5 
Pfisterer M, 67  Shojania KG, 21  Wilson J, 6 
Phillips CO, 70  Simel DL, 21  Wu JY, 9 
Piller LB, 16  Simon GE, 78  Xiao SD, 63 
Pittas AG, 38  Smith B, 18  YusufS , 8, 10 
Pitts SR, 43  Smith BJ, 17  Zanettini  R, 76 
Poldermans D, 20  Smith D, 40  Zhang CX, 63 
Poole Py, 18, 36  Smith TJ, 5  Zhang J, 25 
Pugh JA, 39  Song Y, 25 
Punthakee Z, 38  Sotos JG, A-10 (No. 2) 
MaAyY/JUNE 2007 |V OLUME  146 © NUMBER 3 
ACP JOURNAL CLUB
UBJECT  INDEX 
A  Review: ACE inhibitors and angiotensin-receptor blockers reduce 
Abdomen, acute  diabetes in hypertension and other CV  risk factors,  11 
Review: Opiate administration may alter physical examination  Angiotensin-converting enzyme inhibitors 
findings, but does not increase management errors in acute  Ramipril did not reduce incident diabetes in patients with impaired 
glycemic control,  10 
abdominal pain, 21 
Review: ACE inhibitors and angiotensin-receptor blockers reduce 
Acute disease 
diabetes in hypertension and other CV risk factors,  11 
Review: Exercise interventions reduce length and cost of hospital 
Antiasthmatic agents 
stay in older patients hospitalized for acute conditions, 72 
Review: Long-acting B-agonists increase severe asthma exacerbations 
Adenocarcinoma 
and asthma-related deaths in children and adults,  17 
Perioperative chemotherapy improved survival in resectable 
adenocarcinoma of the stomach or lower esophagus, 2  Antibacterial agents 
Use of different diagnostic methods for ventilator-associated 
Adrenergic O-antagonists 
pneumonia did not affect mortality or targeted antibiotic use, 62 
Review: Medical therapy with calcium-channel blockers or 
Anticoagulants 
a-blockers helps patients to pass urinary stones, 22 
An abnormal D-dimer test result indicated that anticoagulation 
Adrenergic B-agonists 
should be continued, 29 
Review: Anticholinergics, but not B,-agonists, reduce exacerbations 
Fixed-dose, weight-adjusted, unfractionated heparin was as 
requiring hospitalization and respiratory deaths in  COPD, 19 
Review: Long-acting §,-adrenoceptor agonists are effective in poorly  effective and safe as low-molecular-weight heparin for venous 
reversible chronic obstructive pulmonary disease,  18  thromboembolism,  | 
Review:  Long-acting B-agonists increase severe asthma exacerbations  A risk model predicted major bleeding in older patients with atrial 
fibrillation receiving warfarin therapy, 52 
and asthma-related deaths in children and adults, 17 
Adrenergic B-antagonists  Antihypertensive agents 
Discontinuation of medications  1 month after an acute myocardial  Review: Angiotensin-receptor blockers and angiotensin-converting 
enzyme inhibitors have the lowest risk for diabetes, 73 
infarction increased risk for death at 12 months, 47 
No cardiac testing for intermediate-risk patients on B-blockers was  Anti-inflammatory agents, nonsteroidal 
Etoricoxib was noninferior to diclofenac for cardiovascular outcomes 
noninferior to testing before vascular surgery for preventing 
in osteoarthritis and rheumatoid arthritis, 44 
death and nonfatal MI, 20 
Nonsteroidal antiinflammatory drugs did not increase risk for 
Albuterol 
all-cause mortality in osteoarthritis, 77 
Review: Long-acting B,-adrenoceptor agonists are effective in poorly 
Review: Nonselective nonsteroidal anti-inflammatory drugs do not 
reversible chronic obstructive pulmonary disease,  18 
Alcohol drinking  increase risk for cardiovascular events,  12 
Review: Risk for cardiovascular events is increased with rofecoxib, 
Review: High alcohol intake increases mortality in both men and 
diclofenac, and indomethacin, but not celecoxib, 24 
women, 48 
Antineoplastic agents 
Alendronate 
Adjuvant vinorelbine plus cisplatin extended survival longer than 
Continuing alendronate for an additional 5 years maintained bone 
observation in resected non-small-cell lung cancer, 31 
mineral density in postmenopausal women, 64 
Anastrozole had a better risk—benefit profile than tamoxifen as 
Alzheimer disease 
adjuvant treatment for breast cancer in postmenopausal women, 4 
Olanzapine, quetiapine, or risperidone did not differ from placebo 
Perioperative chemotherapy improved survival in resectable 
for Alzheimer disease, 35 
adenocarcinoma of the stomach or lower esophagus, 2 
Amlodipine 
Review: Adding cytotoxic drugs to a chemotherapy regimen 
Diuretics were superior to calcium-channel blockers and short-term 
increases tumor response rates and toxicity, but not survival in 
ACE  inhibitors ior reducing heart failure in hypertension,  16 
metastatic breast cancer, 5 
Analgesics, opioid 
Review: Opiate administration may alter physical examination  Antipsychotic agents 
findings, but does not increase management errors in acute  Olanzapine, quetiapine, or risperidone did not differ from placebo 
for Alzheimer disease, 35 
abdominal pain, 21 
Arrhythmia 
Anemia 
Review: Rofecoxib increases renal events and arrhythmia, but a 
Review: Erythropoietin or darbepoetin for anemia in patients 
COX-2-inhibitor class effect does not exist, 25 
with cancer produces both benefits and harms with no increase 
Arterial occlusive diseases 
in survival, 6 
Simvastatin was cost-effective across a broad range of risk and age 
Angioplasty 
Noninferiority was not shown between stenting and endarterectomy  groups, 50 
Arthritis, rheumatoid 
in severe symptomatic carotid stenosis, 33 
Etoricoxib was noninferior to diclofenac for cardiovascular outcomes 
Urgent revascularization with PCI was more cost-effective than 
in osteoarthritis and rheumatoid arthritis, 44 
CABG in medically refractory, high-risk myocardial ischemia, 49 
Aspirin 
Angiotensin-receptor blockers  Discontinuation of medications  1 month after an acute myocardial 
Ramipril did not reduce incident diabetes in patients with impaired 
infarction increased risk for death at 12 months, 47 
glycemic control,  10 
ACP JOURNAL CLUB  MAY/JUNE 2007 |V OLUME  146 * NUMBER 3
SUBJECT  INDEX 
Review: Low-dose aspirin causes a small increase in gastrointestinal  Cerebrovascular disorders 
bleeding, 13  ABCD, California, and unified ABCD2 risk scores predicted stroke 
Asthma  within 2, 7, and 90 days after TIA, 79 
Review: Long-acting f-agonists increase severe asthma exacerbations  Atorvastatin at 80 mg/d reduced cerebrovascular events more than 
and asthma-related deaths in children and adults, 17  atorvastatin at 10 mg/d in stable coronary heart disease, 30 
Atrial fibrillation  Atorvastatin reduced stroke and CV events after recent stroke or TIA 
A risk model predicted major bleeding in older patients with atrial  in patients with no known coronary heart disease, 7 
fibrillation receiving warfarin therapy, 52  Cholesterol, LDL 
Atorvastatin at 80 mg/d reduced cerebrovascular events more than 
atorvastatin at 10 mg/d in stable coronary heart disease, 30 
B 
Cholinergic antagonists 
Blood glucose  Review: Anticholinergics, but not B,-agonists, reduce exacerbations 
Sitagliptin improved glycemic control and B-cell function in type 2  requiring hospitalization and respiratory deaths in COPD, 19 
diabetes, 39  Cimicifuga 
Bone density  Herbal supplements did not relieve vasomotor symptoms of 
Continuing alendronate for an additional 5 years maintained bone  menopause in women, 65 
mineral density in postmenopausal women, 64  Citalopram 
Breast neoplasms  Citalopram reduced depressive symptoms in coronary artery disease 
10-year follow-up showed benefit of adding radiotherapy to local  with depression, 68 
excision for ductal carcinoma in situ, 3  Colorectal neoplasms, hereditary nonpolyposis 
Anastrozole had a better risk—benefit profile than tamoxifen as adjuvant  The MMRpro model accurately predicted the probability of carrying 
treatment for breast cancer in postmenopausal women, 4  a cancer-susceptibility gene mutation for the Lynch syndrome, 53 
Review: Adding cytotoxic drugs to a chemotherapy regimen increases  Coronary disorders 
tumor response rates and toxicity, but not survival in metastatic  Atorvastatin at 80 mg/d reduced cerebrovascular events more than 
breast cancer, 5  atorvastatin at 10 mg/d in stable coronary heart disease, 30 
Bronchoalveolar lavage  Citalopram reduced depressive symptoms in coronary artery disease 
Use of different diagnostic methods for ventilator-associated 
with depression, 68 
pneumonia did not affect mortality or targeted antibiotic use, 62 
Drug-eluting stents increased risk for late cardiac deaths or 
Bronchodilator agents 
myocardial infarction more than bare-metal stents, 66 
Review: Long-acting B.,-adrenoceptor agonists are effective in poorly 
No cardiac testing for intermediate-risk patients on B-blockers was 
reversible chronic obstructive pulmonary disease,  18  noninferior to testing before vascular surgery for preventing 
death and nonfatal MI, 20 
.&  Nonsteroidal antiinflammatory drugs did not increase risk for 
Calcium-channel blockers  all-cause mortality in osteoarthritis, 77 
Review: Medical therapy with calcium-channel blockers or ot-blockers  Review: Drug-eluting stents for coronary artery disease do not 
helps patients to pass urinary stones, 22  reduce mortality more than bare-metal stents, 66 
Carcinoma  Simvastatin was cost-effective across a broad range of risk and age 
Adjuvant vinorelbine plus cisplatin extended survival longer than  groups, 50 
observation in resected non-small-cell lung cancer, 31  Urgent revascularization with PCI was more cost-effective than 
10-year follow-up showed benefit of adding radiotherapy to local  CABG in medically refractory, high-risk myocardial ischemia, 49 
excision for ductal carcinoma in situ, 3  Critical pathways 
Cardiac surgical procedures  Correction: A nurse-led clinical pathway reduced hospitalizations in 
A bedside tool predicted the need for dialysis after cardiac surgery, 81  nursing home residents with pneumonia, A-11  (No. 2) 
Cardiovascular diseases  A nurse-led clinical pathway reduced hospitalizations in nursing 
Review: Framingham risk scores have variable accuracy in predicting  home residents with pneumonia, 25 
CVD events in different patient populations, 80  Cyclooxygenase-2 inhibitors 
Review: Nonselective nonsteroidal anti-inflammatory  drugs do not  Etoricoxib was noninferior to diclofenac for cardiovascular outcomes 
increase risk for cardiovascular events,  12  in osteoarthritis and rheumatoid arthritis, 44 
Review: Risk for cardiovascular events is increased with rofecoxib,  Review: Risk for cardiovascular events is increased with rofecoxib, 
diclofenac, and indomethacin, but not celecoxib, 24  diclofenac, and indomethacin, but not celecoxib, 24 
Carotid stenosis  Review: Rofecoxib increases renal events and arrhythmia, but a 
Noninferiority was not shown between stenting and endarterectomy  COX-2-inhibitor class effect does not exist, 25 
in severe symptomatic carotid stenosis, 33 
Stenting led to more stroke or death than did endarterectomy in  D 
symptomatic carotid stenosis  > 60%, 32 
Catheterization, central venous  Dementia 
Ultrasonographic guidance increased successful insertion of internal  Community-based occupational therapy improved daily functioning 
jugular vein catheter in the emergency department, 43  in older patients with dementia, 34 
MAY/JUNE 2007 | VOLUME 146 ¢ NUMBER 3  ACP JOURNAL CLUB
SUBJECT  INDEX 
Depression  Pergolide and cabergoline were associated with increased risk for 
Citalopram reduced depressive symptoms in coronary artery disease  newly diagnosed cardiac-valve regurgitation, 75 
with depression, 68  Erythropoietin 
Collaborative care for depression in patients with diabetes increased  Review: Erythropoietin or darbepoetin for anemia in patients with 
depression-free days and had economic benefit, 78  cancer produces both benefits and harms with no increase in 
Diabetes mellitus  survival, 6 
Collaborative care for depression in patients with diabetes increased 
Esophageal neoplasms 
depression-free days and had economic benefit, 78 
Perioperative chemotherapy improved survival in resectable 
How should clinicians interpret results reflecting the effect of an 
adenocarcinoma of the stomach or lower esophagus, 2 
intervention on composite endpoints?, A-12, (No. 3) 
Estrogen replacement therapy 
A lifestyle intervention continued to prevent type 2 diabetes in 
Herbal supplements did not relieve vasomotor symptoms of 
high-risk patients after the program was stopped, 37 
Ramipril did not reduce incident diabetes in patients with impaired  menopause, 65 
Ethanolamines 
glycemic control,  10 
Review: ACE inhibitors and angiotensin-receptor blockers reduce  Review: Long-acting B,-adrenoceptor agonists are effective in poorly 
diabetes in hypertension and other CV risk factors, 1 1  reversible chronic obstructive pulmonary disease,  18 
Review: Angiotensin-receptor blockers and angiotensin-converting  Evidence-based medicine 
enzyme inhibitors have the lowest risk for diabetes, 73  The evolving science of translating research evidence into clinical 
Review: Inhaled insulin provides better glycemic control than oral  practice, A-8 (No. 3) 
hypoglycemic agents but not better than subcutaneous insulin, 38  Making sense of diagnostic test likelihood ratios, A-8—A-9 (No. 2) 
Review: Pioglitazone does not reduce risk for mortality or cardiovascular  Misunderstandings, misperceptions, and mistakes, 
events in type 2 diabetes, 40  A-8—A-9 (No. 1) 
Rosiglitazone reduced type 2 diabetes but increased heart failure in  Resource Corner: Statistical Evidence in Medical Trials: What De the 
patients with impaired glycemic control, 8  Data Really Tell Us?, A-10 (No. 1) 
Simvastatin was cost-effective across a broad range of risk and age  Simplified calculations using likelihood ratios, A-10 (No 2) 
groups, 50  Exercise 
Sitagliptin improved glycemic control and B-cell function in type 2 
A lifestyle intervention continued to prevent type 2 diabetes in 
diabetes, 39  high-risk patients after the program was stopped, 37 
Vildagliptin was noninferior to rosiglitazone for glycemic control in 
No cardiac testing for intermediate-risk patients on B-blockers was 
type 2 diabetes but caused less weight gain, 74 
noninferior to testing before vascular surgery for preventing 
Dibenzothiazepines 
death and nonfatal MI, 20 
Olanzapine, quetiapine, or risperidone did not differ from placebo 
Physical counterpressure maneuvers reduced vasovagal syncope, 41 
for Alzheimer disease, 35 
Review: Exercise interventions reduce length and cost of hospital 
Diclofenac 
Etoricoxib was noninferior to diclofenac for cardiovascular outcomes  stay in older patients hospitalized for acute conditions, 72 
in osteoarthritis and rheumatoid arthritis, 44 
Diet 
A lifestyle intervention continued to prevent type 2 diabetes in 
high-risk patients after the program was stopped, 37  Fenoldopam 
Dipeptidyl peptidases  Review: Fenoldopam reduces acute kidney  injury and death in critical 
Sitagliptin improved glycemic control and B-cell function in type 2  illness, 58 
diabetes, 39  Fibrin fibrinogen degradation products 
Disease transmission, professional-to-patient  An abnormal D-dimer test result indicated that anticoagulation 
Encouraging influenza vaccination for nursing home staff reduced  should be continued, 29 
mortality and influenza-like illness in the residents, 61  Fibrinolytic agents 
Dopamine agonists  A simple risk score discriminated between patients at low or high 
Pergolide and cabergoline increased risk for valvular heart disease in  risk for adverse events during therapy for acute DVT, 51 
Parkinson's disease, 76  Folic acid 
Pergolide and cabergoline were associated with increased risk for 
Daily folic acid supplementation for 3 years improved cognitive 
newly diagnosed cardiac-valve regurgitation, 75 
function in older persons, 71 
E  Fractures, bone 
Continuing alendronate for an additional 5 years maintained bone 
Endarterectomy, carotid 
mineral density in postmenopausal women, 64 
Noninferiority was not shown between stenting and endarterectomy 
in severe symptomatic carotid stenosis, 33 
Stenting led to more stroke or death than did endarterectomy in  G 
symptomatic carotid stenosis 2 60%, 32 
Genetic screening 
Ergolines 
Pergolide and cabergoline increased risk for valvular heart disease in  The MMRpro model accurately predicted the probability of carrying a 
Parkinson's disease, 76  cancer-susceptibility gene mutation for the Lynch syndrome, 53 
ACP JOURNAL CLUB  MAY/JUNE 2007 | VOLUME  146 * NUMBER 3
SUBJECT  INDEX 
H  Review: Statin monotherapy is safe in hyperlipidemia except for 
Headache  increased risk for transaminase elevation, 70 
Review: History and physical examination can accurately identify  Simvastatin was cost-effective across a broad range of risk and age 
migraine and the need for neuroimaging in patients with  groups, 50 
headache, 23  Hypertension 
Health services  Diuretics were superior to calcium-channel blockers and short-term 
ACE  inhibitors for reducing heart failure in hypertension, 16 
Encouraging influenza vaccination for nursing home staff reduced 
mortality and influenza-like illness in the residents, 61  Hypoglycemic agents 
Heart disease  How should clinicians interpret results reflecting the effect of an 
Diuretics were superior to calcium-channel blockers and short-term  intervention on composite endpoints?, A-12 (No. 3) 
ACE inhibitors for reducing heart failure in hypertension,  16  Review: Inhaled insulin provides better glycemic control than oral 
Pergolide and cabergoline increased risk for valvular heart disease in ’  hypoglycemic agents but not better than subcutaneous insulin, 38 
Parkinson's disease, 76  Review: Pioglitazone does not reduce risk for mortality or 
Pergolide and cabergoline were associated with increased risk for  cardiovascular events in type 2 diabetes, 40 
newly diagnosed cardiac-valve regurgitation, 75  Rosiglitazone reduced type 2 diabetes but increased heart failure in 
Helicobacter pylori  patients with impaired glycemic control, 8 
Review: Eradication therapy supplemented by probiotics increased 
eradication rates and reduced side effects in H. pylori infection, 63 
Hemodiafiltration 
Continuous venovenous hemodiafiltration and intermittent  Influenza 
hemodialysis did not differ for improving survival in acute renal  Encouraging influenza vaccination for nursing home staff reduced 
failure with multiorgan dysfunction,  15  mortality and influenza-like illness in the residents, 61 
Continuous venovenous hemodiafiltration increased survival more  Inactivated influenza vaccine prevented influenza in healthy adults, 60 
than did continuous hemofiltration in acute renal failure, 14  Insulin 
Hemorrhage  How should clinicians interpret results reflecting the effect of an 
Review: Low-dose aspirin causes a small increase in gastrointestinal  intervention on composite endpoints?, A-12 (No. 3) 
bleeding, 13  Review: Inhaled insulin provides better glycemic control than oral 
A risk model predicted major bleeding in older patients with atrial  hypoglycemic agents but not better than subcutaneous insulin, 38 
fibrillation receiving warfarin therapy, 52  Ischemic attack, transient 
A simple risk score discriminated between patients at low or high  Atorvastatin  reduced stroke and  CV events after recent stroke or TIA 
risk for adverse events during therapy for acute DVT, 51 
in patients with no known  coronary  heart disease, 7 
Heparin, low-molecular-weight 
The ABCD, California, and unified ABCD2 risk scores predicted 
Fixed-dose, weight-adjusted, unfractionated heparin was as 
stroke within 2, 7, and 90 days after TIA, 79 
effective and safe as low-molecular-weight heparin for venous 
thromboembolism,  1 
Heptanoic acids  K 
Atorvastatin at 80 mg/d reduced cerebrovascular events more than 
atorvastatin at 10 mg/d in stable coronary  heart disease,  30  Kidney failure 
Atorvastatin reduced stroke and  CV events after recent stroke or  TIA  \ bedside tool predicted the need for dialysis after cardiac surgery, 81 
in patients with no known coronary  heart disease, 7  Continuous venovenous hemodiafiltration and intermittent 
Hospitalization  hemodialysis did not differ for improving surv ival in acute renal 
Correction: A nurse-led clinical pathway  reduced hospitalizations in  failure with multiorgan dysfunction,  15 
nursing home residents with pneumonia,  A-11  (No. 2)  Continuous venovenous hemodiafiltration  increased survival more 
A nurse-led clinical pathway  reduced hospitalizations in nursing  than did continuous hemofiltration  in acute renal failure,  14 
home residents with pnemonia, 25  Review: Fenoldopam reduces acute  kidney injury and death in critical 
Encouraging influenza vaccination for nursing home staff reduced  illness, 58 
mortality and influenza-like illness in the residents, 61 
Review: Exercise interventions reduce length and cost of hospital 
stay in older patients hospitalized for acute conditions, 72 
Review: Long-acting f-agonists increase severe asthma exacerbations  Lisinopril 
Diuretics were superior to calcium-channel blockers and short-term 
and asthma-related deaths in children and adults,  17 
ACE  inhibitors for reducing heart failure in hypertension,  16 
Hot flashes 
Herbal supplements did not relieve vasomotor symptoms of  Lung diseases 
menopause, 65  \djuvant vinorelbine plus cisplatin extended survival longer than 
Hydroxymethylglutaryl-CoA reductase inhibitors  observation in resected non-small-cell lung cancer, 31 
Atorvastatin reduced stroke and CV events after recent  stroke or  TIA  Procalcitonin level—guided treatment  reduced antibiotic use in 
in patients with no known coronary  heart disease, 7  exacerbations  of COPD, 57 
Discontinuation of medications  1 month after an acute myocardial  Review:  Long-acting B,-adrenoceptor agonists are effective in poorly 
infarction increased risk for death at 12 months, 47  reversible chronic obstructive pulmonary disease,  18 
MAY/JUNE 2007 |V OLUME  146 * NUMBER 3  ACP JOURNAL CLUB
SUBJECT  INDEX 
M  Pergolide 
Medical informatics  Pergolide and cabergoline increased risk for valvular heart disease in 
The evolving science of translating research evidence into clinical  Parkinson's disease, 76 
Pergolide and cabergoline were associated with increased risk for 
practice, A-8 (No. 3) 
newly diagnosed cardiac-valve regurgitation, 75 
Meningitis, bacterial 
Pharmaceutical services 
Review: Success of lumbar puncture is enhanced by reinserting the 
Periodic telephone counseling for polypharmacy improved 
stylet before removing the needle, 42 
compliance and reduced mortality, 9 
Microbial sensitivity tests 
Physical examination 
Microscopic-observation drug-susceptibility assay was more se..sitive 
Review: Opiate administration may alter physical examination 
than standard tests for diagnosing tuberculosis, 45 
findings, but does not increase management errors in acute 
Mycobacterium tuberculosis 
abdominal pain, 21 
Microscopic-observation drug-susceptibility assay was more sensitive 
Phytotherapy 
than standard tests for diagnosing tuberculosis, 45 
Herbal supplements did not relieve vasomotor symptoms of 
Myocardial disorders 
Discontinuation of medications  | month after an acute myocardial  menopause in women, 65 
Platelet aggregation inhibitors 
infarction increased risk for death at 12 months, 47 
Drug-eluting stents increased risk for late cardiac death or 
Myocardial ischemia 
myocardial infarction more than bare-metal stents, 67 
Urgent revascularization with PCI was more cost-effective than 
Review: Drug-eluting stents for coronary artery disease do not 
CABG in medically refractory, high-risk myocardial ischemia, 49 
reduce mortality more than bare-metal stents, 66 
Pneumonia 
N  Correction: A nurse-led clinical pathway reduced hospitalizations in 
Neoplasms  nursing home residents with pneumonias A-11  (No. 2) 
Review: Erythropoietin or darbepoetin for anemia in patients with  A nurse-led clinical pathway reduced hospitalizations in nusring 
cancer produces both benefits and harms with no increase in  home residents with pneumonia, 25 
survival, 6  Review: Trials of injectable pneumococcal vaccines do not show 
10-year follow-up showed benefit of adding radiotherapy to local  effectiveness in chronic obstructive pulmonary disease, 36 
excision for ductal carcinoma in situ, 3  Use of different diagnostic methods for ventilator-associated 
Nitrites  pneumonia did not affect mortality or targeted antibiotic use, 62 
Anastrozole had a better risk—benefit profile than tamoxifen as adjuvant  Postoperative complications 
treatment for breast cancer in postmenopausal women, 4  Ultrasonographic guidance increased successful insertion of internal 
Nursing homes  jugular vein catheter in the emergency department, 43 
Correction: A nurse-led clinical pathway reduced hospitalizations in  Pregnancy outcome 
nursing home residents with pneumonia, A-11  (No. 2)  How should clinicians interpret results reflecting the effect of an 
Encouraging influenza vaccination for nursing home staff reduced  intervention on composite endpoints?, A-12 (No. 3) 
mortality and influenza-like illness in the residents, 61  Prepaid health plans 
A nurse-led clinical pathway reduced hospitalizations in nursing  Collaborative care for depression in patients with diabetes increased 
home residents with pneumonia, 25  depression-free days and had economic benefit, 78 
Probiotics 
Review: Eradication therapy supplemented by probiotics increased 
O  eradication rates and reduced side effects in H. pylori infection, 63 
Occupational therapy  Professional-family  relations 
Community-based occupational therapy improved daily functioning  A communication strategy and brochure reduced the burden of 
in older patients with dementia, 34  bereavement on relatives of patients dying in the intensive care 
Osteoarthritis  unit, 69 
Etoricoxib was noninferior to diclofenac for cardiovascular outcomes  Psychotherapy, brief 
in osteoarthritis and rheumatoid arthritis, 44  Citalopram reduced depressive symptoms in coronary artery disease 
Nonsteroidal antiinflammatory drugs did not increase risk for  with depression, 68 
all-cause mortality in osteoarthritis, 77  Pulmonary disease 
Outcome assessment  (health care)  Fixed-dose, weight-adjusted, unfractionated heparin was as 
How should clinicians interpret results reflecting the effect of an  effective and safe as low-molecular-weight heparin for venous 
intervention on composite endpoints?, A-12 (No. 3)  thromboembolism,  | 
Persistent right ventricular dysfunction increased risk for recurrent 
venous thromboembolism after acute pulmonary embolism, 4¢ 
P  Review: Anticholinergics, but not B,-agonists, reduce exacerbations 
Parkinson disease  requiring hospitalization and respiratory deaths in COPD,  19 
Pergolide and cabergoline increased risk for valvular heart disease in  Review: Trials of injectable pneumococcal vaccines do not show 
Parkinson's disease, 76  effectiveness in chronic obstructive pulmonary disease, 36 
ACP JOURNAL CLUB  MAY/JUNE 2007 | VOLUME  146 ¢ NUMBER 3
SUBJECT  INDEX 
A simple risk score discriminated between patients at low or high  Stenting led to more stroke or death than did endarterectomy in 
risk for adverse events during therapy for acute DVT, 51  symptomatic carotid stenosis 2 60%, 32 
An abnormal D-dimer test result indicated that anticoagulation  Stomach neoplasms 
should be continued, 29  Perioperative chemotherapy improved survival in resectable 
Pyridines  adenocarcinoma of the stomach or lower esophagus, 2 
Etoricoxib was noninferior to diclofenac for cardiovascular outcomes  Stress disorders, posttraumatic 
in osteoarthritis and rheumatoid arthritis, 44  A communication strategy and brochure reduced the burden of 
Pyrroles  bereavement on relatives of patients dying in the intensive care 
Atorvastatin at 80 mg/d reduced cerebrovascular events more than  unit, 69 
atorvastatin at 10 mg/d in stable coronary heart disease, 30  Sulfones 
Atorvastatin reduced stroke and CV events after recent stroke or TIA  Etoricoxib was noninferior to diclofenac for cardiovascular outcomes 
in patients with no known coronary heart disease, 7  in osteoarthritis and rheumatoid arthritis, 44 
Syncope, vasovagal 
R  Physical counterpressure maneuvers reduced vasovagal syncope, 41 
Receptor, serotonin, 5-HT2B 
Pergolide and cabergoline increased risk for valvular heart disease in  : 
Parkinson's disease, 76  Tamoxifen 
Pergolide and cabergoline were associated with increased risk for  Anastrozole had a better risk—benefit profile than tamoxifen as adjuvant 
newly diagnosed cardiac-valve regurgitation, 75  treatment for breast cancer in postmenopausal women, 4 
Renal disease  Thiazolidinediones 
A bedside tool predicted the need for dialysis after cardiac surgery, 81 
Review: Pioglitazone does not reduce risk for mortality or cardiovascular 
Continuous venovenous hemodiafiltration and intermittent  events in type 2 diabetes, 40 
hemodialysis did not differ for improving survival in acute renal 
Ticlopidine 
failure with multiorgan dysfunction, 15 
Drug-eluting stents increased risk for late cardiac death or myocardial 
Continuous venovenous hemodiafiltration increased survival more 
infarction more than bare-metal stents, 67 
than did continuous hemofiltration in acute renal failure, 14 
Triazoles 
Review: Medical treatment and revascularization may be similar in 
Anastrozole had a better risk—benefit profile than tamoxifen as adjuvant 
atherosclerotic renal artery stenosis, 59 
treatment for breast cancer in postmenopausal women, 4 
Review: Rofecoxib increases renal events and arrhythmia, but a 
Tuberculosis 
COX-2-inhibitor class effect does not exist, 25 
Microscopic-observation drug-susceptibility assay was more sensitive 
Risperidone 
than standard tests for diagnosing tuberculosis, 45 
Olanzapine, quetiapine, or risperidone did not differ from placebo 
for Alzheimer disease, 35 
Rosiglitazone  U 
Vildagliptin was noninferior to rosiglitazone for glycemic control in 
Ultrasonography, interventional 
type 2 diabetes but caused less weight gain, 74 
Ultrasonographic guidance increased successful insertion of internal 
jugular vein catheter in the emergency department, 43 
Urinary calculi 
Simvastatin  Review: Medical therapy with calcium-channel blockers or &-blockers 
Simvastatin was cost-effective across a broad range of risk and age  helps patients to pass urinary stones, 22 
groups, 50 
Spinal puncture 
V 
Review: Success of lumbar puncture is enhanced by reinserting the 
stylet before removing the needle, 42  Vasomotor system 
Sputum  Herbal supplements did not relieve vasomotor symptoms of 
Microscopic-observation drug-susceptibility assay was more sensitive  menopause in women, 65 
than standard tests for diagnosing tuberculosis, 45  Venous thrombosis 
Statistics  An abnormal D-dimer test result indicated that anticoagulation 
How should clinicians interpret results reflecting the effect of an  should be continued, 29 
intervention on composite endpoints?, A-12 (No. 3)  Fixed-dose, weight-adjusted, unfractionated heparin was as 
Stents  effective and safe as low-molecular-weight heparin for venous 
Drug-eluting stents increased risk for late cardiac death or myocardial  thromboembolism,  1 
infarction more than bare-metal stents, 67  A simple risk score discriminated between patients at low or high 
Noninferiority was not shown between stenting and endarterectomy  risk for adverse events during therapy for acute DVT, 51 
in severe symptomatic carotid stenosis, 33  Ventricular dysfunction, right 
Review: Drug-eluting stents for coronary artery disease do not  Persistent right ventricular dysfunction increased risk for recurrent 
reduce mortality more than bare-metal stents, 66  venous thromboembolism after acute pulmonary embolism, 46 
MAY/JUNE 2007 |V OLUME  146 * NUMBER 3  ACP JOURNAL CLUB