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About A Network Map of Interleukin-10 Signaling Pathway: Bits and Bytes
This document summarizes a study that mapped out the Interleukin-10 (IL-10) signaling pathway. The study manually annotated 37 molecules and 76 reactions in the IL-10 pathway based on literature. IL-10 is an anti-inflammatory cytokine secreted by immune cells that binds to a receptor complex and activates JAK/STAT and Akt cascades. Dysregulation of IL-10 signaling has been linked to cancer progression and survival of intracellular pathogens. The study developed a pathway resource in NetPath that maps the IL-10 signaling interactions.
Detailed Information
Author: | ['Kleber Felipe'] |
---|---|
Publication Year: | 2020 |
Pages: | 7 |
Language: | English |
Format: | |
Price: | FREE |
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