Small Animal Clinical Pharmacology and Therapeutics, 2nd Edition

4361 Pages·2011·17.23 MB·English

by  Dawn Merton Boothe DVM MS PhD DACVIM DACVCP

Small Animal Clinical
Pharmacology & Therapeutics
Second Edition
Dawn Merton Boothe, DVM, MS, PhD, DACVIM, DACVP
Professor, Department of Physiology and Pharmacology, College of
Veterinary Medicine
Director, Clinical Pharmacology Laboratory, Auburn University, Auburn,
Alabama
Copyright © 2012, 2001 by Elsevier Inc.
Saunders
Front Matter
Second Edition
Small Animal
Clinical Pharmacology & Therapeutics
Dawn Merton Boothe, DVM, MS, PhD, DACVIM, DACVP
Professor, Department of Physiology and Pharmacology, College
of Veterinary Medicine
Director, Clinical Pharmacology Laboratory, Auburn University,
Auburn, Alabama
Copyright
3251 Riverport Lane
St. Louis, Missouri 63043
SMALL ANIMAL CLINICAL PHARMACOLOGY AND THERAPEUTICS
ISBN: 978-0-72160555-5
Copyright © 2012, 2001 by Saunders, an imprint of Elsevier Inc.
All rights reserved. No part of this publication may be reproduced or
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Notice
Knowledge and best practice in this field are constantly changing. As new research and
experience broaden our understanding, changes in research methods, professional practices,
or medical treatment may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge
in evaluating and using any information, methods, compounds, or experiments described
herein. In using such information or methods they should be mindful of their own safety and
the safety of others, including parties for whom they have a professional responsibility.
With respect to any drug or pharmaceutical products identified, readers are advised to
check the most current information provided (i) on procedures featured or (ii) by the
manufacturer of each product to be administered, to verify the recommended dose or
formula, the method and duration of administration, and contraindications. It is the
responsibility of practitioners, relying on their own experience and knowledge of their
patients, to make diagnoses, to determine dosages and the best treatment for each individual
patient, and to take all appropriate safety precautions.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or
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Library of Congress Cataloging-in-Publication Data
Small animal clinical pharmacology and therapeutics/[edited by]
Dawn Merton Boothe. -- 2nd ed.
p.; cm.
Rev. ed. of: Small animal clinical pharmacology and
therapeutics/Dawn Merton Boothe. c2001.
Includes bibliographical references and index.
ISBN 978-0-72160555-5 (pbk.: alk. paper) 1. Dogs--Diseases--
Treatment. 2. Cats--Diseases--Treatment. 3. Veterinary pharmacology.
I. Boothe, Dawn Merton. II. Boothe, Dawn Merton. Small animal
clinical pharmacology and therapeutics.
[DNLM: 1. Dog Diseases--drug therapy. 2. Cat Diseases--drug
therapy. 3. Veterinary Drugs. SF 991]
SF991.B676 2012
636.7'0895--dc22 2011004138
Vice President and Publisher: Linda Duncan Acquisitions Editor: Heidi
Pohlman Senior Developmental Editor: Shelly Stringer Publishing Services
Manager: Julie Eddy Senior Project Manager: Celeste Clingan Design
Direction: Margaret Reid
Printed in the United States of America
Last digit is the print number: 9 8 7 6 5 4 3 2 1
Contributors
Paul R. Avery, VMD, PhD, Associate Professor, Department of
Microbiology, Immunology and Pathology College of Veterinary
Medicine, Colorado State University, Fort Collins, Colorado
Biologic Response Modifiers: Interferons, Interleukins, Recombinant
Products, and Liposomal Products
Ellen N. Behrend, VMD, PhD, DACVIM, Professor, Department of
Clinical Sciences College of Veterinary Medicine, Auburn
University, Auburn, Alabama
Drug Therapy for Endocrinopathies
Harry W. Boothe, DVM, Professor, Department of Clinical Sciences
College of Veterinary Medicine, Auburn University, Auburn,
Alabama
Disinfectants, Antiseptics, and Related Biocides
Janice L. Cain, DVM, DACVIM, Staff Veterinarian, Bishop Ranch
Veterinary Center, San Ramon, California
Rational Use of Reproductive Hormones
Tanya D. Civco, DVM, DACVIM, Associate Professor, Department of
Clinical Sciences College of Veterinary Medicine, Auburn
University, Auburn, Alabama
Drug Therapy for Endocrinopathies
Tad B. Coles, DVM, Institutional Animal Care and Use Committee
Veterinarian, Research and Graduate Studies, Kansas University,
Lawrence, Kansas, Freelance Medical Writing and Regulatory
Consulting, Overland Park, Kansas
Drugs for the Treatment of Helminth Infections – Anthelmintics
Autumn P. Davidson, DVM, MS, DACVIM, Clinical Professor
Department of Medicine and Epidemiology, School of Veterinary
Medicine University of California, Davis, California, Staff Internist,
Department of Internal Medicine, VCA Animal Care Center of
Sonoma, Rohnert Park, California
Rational Use of Reproductive Hormones
Reid P. Groman, DVM, DACVIM, DACVECC, Department of Clinical
Studies School of Veterinary Medicine, University of Pennsylvania,
Philadelphia, Pennsylvania
Fluids, Electrolytes, and Acid-Base Therapy
Sophie A. Grundy, BVSc (Hons), MACVSc, DACVIM, Graduate
Student Researcher, Department of Population Health and
Reproduction University of California, Davis, California,
Veterinarian, Internal Medicine and Reproduction, VCA
Sacramento Animal Medicine Group, Carmichael, California
Rational Use of Reproductive Hormones
Robert A. Kennis, DVM, MS, DACVD, Associate Professor,
Department of Clinical Sciences College of Veterinary Medicine,
Auburn University, Auburn, Alabama
Dermatologic Therapy
India F. Lane, DVM, MS, EdD, Associate Professor of Medicine
Director of Educational Enhancement, Department of Small Animal
Clinical Sciences College of Veterinary Medicine, The University of
Tennessee, Knoxville, Tennessee, Internist, W.W. Armistead
Veterinary Teaching Hospital College of Veterinary Medicine, The
University of Tennessee, Knoxville, Tennessee
Treatment of Urinary Disorders
Randy C. Lynn, DVM, MS, DACVP, Director, Professional Services
Group, IDEXX Pharmaceuticals, Inc., Greensboro, North Carolina
Drugs for the Treatment of Protozoal Infections
Drugs for the Treatment of Helminth Infections – Anthelmintics
Elizabeth A. Martinez, DVM, DACVA, Associate Professor,
Department of Small Animal Clinical Sciences College of
Veterinary Medicine, Texas A&M University College Station, Texas
Anesthetic Agents
Muscle Relaxants
Katrina L. Mealey, DVM PhD, DACVIM, DACVCP, Professor,
Department of Veterinary Clinical Sciences College of Veterinary
Medicine, Washington State University, Pullman, Washington
Pharmacogenetics
Antiinflammatory Drugs
Glucocorticoid and Mineralocorticoids
Jennifer E. Stokes, DVM, DACVIM, Clinical Associate Professor
Small Animal Clinical Sciences, College of Veterinary Medicine
University of Tennessee, Knoxville, Tennessee