Table Of ContentRespiratory Regulation – Clinical Advances
Advances in Experimental Medicine and Biology
Editorial Board:
IRUN R. COHEN, The Weizmann Institute of Science, Rehovot, Israel
ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA
JOHN D. LAMBRIS, University of Pennsylvania, Philadelphia, PA, USA
RODOLFO PAOLETTI, University of Milan, Milan, Italy
For further volumes:
http://www.springer.com/series/5584
Mieczyslaw Pokorski
Editor
Respiratory Regulation – Clinical
Advances
Editor
Mieczyslaw Pokorski
Polish Academy of Sciences
Medical Research Center
Department of Respiratory Research
Warsaw, Poland
ISSN 0065-2598
ISBN 978-94-007-4545-2 ISBN 978-94-007-4546-9 (eBook)
DOI 10.1007/978-94-007-4546-9
Springer Dordrecht Heidelberg New York London
Library of Congress Control Number: 2012943590
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Preface
The book contains the articles related to the clinical advances in the regulation of the respiratory
system. The research presented herein was communicated and discussed at the International
Conference ‘Advances in Pneumology,’ which was held in Bonn, Germany, on June 17–18, 2011. The
articles are a selection of peer-reviewed manuscripts to demonstrate the scope of the issues tackled at
the conference. The conference is thought as a merger between basic and clinical research concerning
respiratory medicine, neural and chemical respiratory regulation, and the mutual relationship between
respiration and other neurobiological functions. Clinical pathophysiology of the respiratory system is
always at the core of these meetings. The topics included lung function, hypoxic lung pathologies,
pharmacotherapy, epidemiology, and cardiovascular-respiratory interactions, particularly during
sleep. Other essential topics of interest were infections and in fl ammatory conditions exempli fi ed by
asthma and chronic obstructive pulmonary disease (COPD), respiratory allergy and cough, and also
psychosomatic issues which broadened the scope of the conference. In the articles presented in this
volume, the cutting-edge knowledge is communicated and discussed by prominent experts in the
areas of science outlined above. I want to thank all the speakers at the conference and the authors and
reviewers of the articles; their contributions certainly will enhance the value of this volume.
The ‘Advances in Pneumology’ is an annual conference organized alternately in Poland and Germany.
It refers to the long-standing contacts between Polish and German clinicians and researchers in the
fi eld of respiration. The contacts have begun decades ago from the common interest in prophylaxis and
treatment of respiratory ailments in coal miners and in populations inhabiting the mining regions of
both countries. Nowadays, the coal mining is limited, but the diseases and clinical problems persist.
The 2011 conference was the fruit of many collaborative efforts. The Local Organizing Committee
was headed by Dr. Rüdiger Siekmeier of the Federal Institute for Drugs and Medical Devices (BfArM)
in Bonn, Germany. I am indebted to him for his efforts and to all those who extended a helping hand
and advice in the organization, particularly Prof. Dr. med. Kurt Rasche of HELIOS Klinikum
Wuppertal Lungenzentrum, Klinik für Pneumologie, Allergologie, Schlaf- und Beatmungsmedizin
and Ms. Anke Hastenrath of Wuppertal, and Dr. Tadeusz M. Zielonka of Warsaw Medical University
and the Polish Respiratory Society in Warsaw, Poland.
I also want to thank the non-pro fi t research and academic institution which kindly cooperated and
supported the organization of the conference and the publication of this book, particularly the Medical
Research Center of the Polish Academy of Sciences in Warsaw, the Polish Respiratory Society, and
the Rhein-Ruhr-Stiftung in Essen. Finally, I am also grateful to Mr. Max Haring, Ph.D., and Ms. Tanja
van Gaans of Springer for their expert management of the production process of this book.
v
vi Preface
Due to the efforts of all involved in the conference, the participants could not only bene fi t from
scienti fi c knowledge and contacts but also could enjoy the vibrant Bonn’s life. It had been decided at
the conference that the next conference of this series will be held in the city of Wroclaw in southwest
Poland on October 5–6, 2012; details can be accessed at http://www.pneumology.pl.
Warsaw, Poland Mieczyslaw Pokorski
Contents
1 Assessment of Airway Hyperresponsiveness:
Comparison of Spirometry and Body Plethysmography ................................................ 1
F. Nensa, N. Kotschy-Lang, H.-J. Smith, W. Marek, and R. Merget
2 Hospital Management of Patients with Exacerbation
of Severe Chronic Obstructive Pulmonary Disease ......................................................... 11
Beata Chmielowicz-Frontczak, Bernard Panaszek, and Andrzej Obojski
3 Pulmonary Rehabilitation in Patients Referred for Lung Transplantation .................. 19
D. Jastrzebski, M. Ochman, D. Ziora, L. Labus, K. Kowalski, J. Wyrwol,
W. Lutogniewska, M. Maksymiak, B. Ksiazek, A. Magner, A. Bartoszewicz,
P. Kubicki, G. Hydzik, A. Zebrowska, and J. Kozielski
4 Effects of Nasal Insufflation on Arterial Gas Exchange and Breathing
Pattern in Patients with Chronic Obstructive Pulmonary Disease
and Hypercapnic Respiratory Failure .............................................................................. 27
Georg Nilius, Karl-Josef Franke, Ulrike Domanski, Karl-Heinz Rühle,
Jason P. Kirkness, and Hartmut Schneider
5 Exposure to Traffic-Related Air Pollutants as a Risk of Airway Obstruction .............. 35
Artur J. Badyda, Piotr Dabrowiecki, Wojciech Lubinski,
Piotr O. Czechowski, and Grzegorz Majewski
6 Occupational Immediate-Type Allergic Asthma due to Potassium
Tetrachloroplatinate in Production of Cytotoxic Drugs .................................................. 47
E. Thanasias, I. Polychronakis, V. van Kampen, T. Brüning, and R. Merget
7 Comparison of Different Non-invasive Methods
for Detection of Allergic Asthma ....................................................................................... 55
M. Raulf-Heimsoth, V. van Kampen, E. Heinze, S. Bernard, G. Borowitzki,
S. Freundt, K. Sucker, C. Eliakopoulos, A. Nienhaus, T. Brüning, and R. Merget
8 Deep Nasal Inspirations Increase the Cough Threshold
in Children with Mild Asthma ........................................................................................... 65
R. Pecova, T. Michnova, J. Fabry, T. Zatko, M. Neuschlova,
P. Klco, J. Hanacek, M. Tatar, and Z. Tomori
vii
viii Contents
9 Reproducibility of Sensitivity to Capsaicin Assessed
by Single Breath Inhalation Methodology ........................................................................ 71
Frank Hoffmeyer, Kirsten Sucker, Nina Rosenkranz, Hans Berresheim,
Christian Monse, Thomas Brüning, and Jürgen Bünger
10 Occupational Non-immediate Type Allergic Asthma
due to Ammonium Persulfate ............................................................................................ 79
Ioannis Polychronakis, Efthimios Thanasias,
Monika Raulf-Heimsoth, and Rolf Merget
11 Bronchial Allergen Challenges: Doubling or Quadrupling Dose Steps? ....................... 85
S. Mousalli, V. van Kampen, and R. Merget
12 Evaluation of Laryngopharyngeal Reflux in Pediatric Patients
with Asthma Using a New Technique of Pharyngeal pH-Monitoring ............................ 89
A. Banaszkiewicz, L. Dembinski, A. Zawadzka-Krajewska,
M. Dziekiewicz, P. Albrecht, M. Kulus, and A. Radzikowski
13 Latent Airway Hyperresponsiveness: A Phenomenon
Bordering Bronchial Asthma Definition ........................................................................... 97
Lubomir Legath, Slavomir Perecinsky, Marek Varga,
Martin Orolin, Zoltan Tomori, and Jaroslav Legath
14 Impact of Daytime Sleepiness on Rehabilitation Outcome in the Elderly ..................... 103
H. Frohnhofen, R. Popp, K. Frohnhofen, and S. Fulda
15 Pulmonary Physiotherapy in Patients with Bronchial Asthma ...................................... 111
Grazyna Osiadlo, Michal Plewa, Aleksandra Zebrowska, and Zbigniew Nowak
16 Hypoxemia During Bilevel Positive Airway Pressure Treatment
in Patients with Obstructive Sleep Apnea Syndrome
and Chronic Respiratory Insufficiency ............................................................................. 117
Anna Brzecka, Pawel Piesiak, Monika Kosacka, and Renata Jankowska
17 Validation of the Essener Questionnaire of Age
and Sleepiness in the Elderly Using Pupillometry ........................................................... 125
H. Frohnhofen, S. Fulda, K. Frohnhofen, and R. Popp
18 Lung Function at Age 18–25 Years: A Comparison
of Different Reference Value Systems ............................................................................... 133
E. Marek, J. Volke, H.-J. Smith, B. Serbetci, H. Kalhoff,
N. Kotschy-Lang, R. Merget, and W. Marek
19 Pulmonary Function Impairment in Patients Undergoing
Allogeneic Hematopoietic Cell Transplantation............................................................... 143
Pawel Piesiak, Ewa Gorczynska, Anna Brzecka, Monika Kosacka,
and Renata Jankowska
20 Lung Impairment in Scleroderma ..................................................................................... 149
T. Piorunek, B. Kuznar-Kaminska, S. Cofta, H. Batura-Gabryel,
D. Poplawski, D. Majewski, M. Puszczewicz, and E. Wysocka
21 Severity of Nocturnal Cardiac Arrhythmias Correlates
with Intensity of Sleep Apnea in Men ............................................................................... 155
E. Szaboova, D. Holoubek, Z. Tomori, P. Szabo, V. Donic, and B. Stancak
Contents ix
22 b2-Adrenergic Receptor Gene Polymorphism and Response
to Bronchodilating Treatment Evaluated by Spirometry ................................................ 169
I. Poziomkowska-Gesicka, A. Gawlikowska-Sroka, E. Dzieciolowska-Baran,
I. Teul, G. Adler, A. Ciechanowicz, and M. Kurek
23 Costs of Smoking-Attributable Productivity Losses in Poland ....................................... 179
Joanna Lasocka, Michal Jakubczyk, and Rüdiger Siekmeier
24 Cigarette Smoking Among Students and the Influence
of Legal Regulations on Passive Smoking ......................................................................... 189
A. Gawlikowska-Sroka, E. Dzieciolowska-Baran, J. Szczurowski,
I. Teul, I. Poziomkowska-Gesicka, and E. Kamienska
25 Medical Students’ Aptitude Toward Smoking
in Warsaw, Strasbourg and Teheran ................................................................................. 195
Rafal Machowicz, Joanna Ciechanska, Katarzyna Zycinska, Nastaran Mahboobi,
Emilia Wnekowicz, Michael H. Obrowski, and Tadeusz M. Zielonka
26 Epidemiology of Pertussis in an Urban Region of Poland:
Time for a Booster for Adolescents and Adults ................................................................ 203
Aneta Nitsch-Osuch, Ernest Kuchar, Grazyna Modrzejewska,
Iwona Pirogowicz, Katarzyna Zycinska, and Kazimierz Wardyn
27 Rhinitis as a Cause of Respiratory Disorders During Pregnancy .................................. 213
Edyta Dzieciolowska-Baran, Iwona Teul-Swiniarska,
Aleksandra Gawlikowska-Sroka, Iwona Poziomkowska-Gesicka,
and Zbigniew Zietek
28 Subglottic and Tracheal Stenosis due to Wegener’s Granulomatosis ............................ 221
K. Zycinska, K. Wardyn, T.M. Zielonka, A. Nitsch-Osuch,
S. Zarzycki, U. Demkow, W. Lukas, and I. Pirogowicz
29 Pulmonary Aspergillosis: Therapeutic Management
and Prognostic Factors from 16 Years of Monocenter Experience ................................ 225
Stefan Pabst, Michael Krüger, Dirk Skowasch, H. Zhou, Jens Bürmann,
and Marcel Kaminski
30 Influence of Rapid Influenza Test on Clinical Management
of Children Younger than Five with Febrile Respiratory
Tract Infections ................................................................................................................... 237
Aneta Nitsch-Osuch, Ilona Stefanska, Ernest Kuchar, Lidia B. Brydak,
Iwona Pirogowicz, Katarzyna Zycinska, and Kazimierz Wardyn
31 Influenza Immunization Rates in Children and Teenagers in Polish Cities:
Conclusions from the 2009/2010 Season ........................................................................... 243
Ernest Kuchar, Aneta Nitsch-Osuch, Katarzyna Zycinska,
Katarzyna Miskiewicz, Leszek Szenborn, and Kazimierz Wardyn
32 Pharmacotherapy for Sarcoidosis: An Example of an Off-Label Procedure ................ 251
A. Zimmermann, A. Dubaniewicz, and J.M. Slominski
33 Invasive Pneumococcal Bacteremia in a 9-Year-Old Boy
Caused by Serotype 1: Course, Treatment and Costs ..................................................... 257
Teresa Jackowska, Joanna Zaleska-Ponganis, and Dominik Dziurda
x Contents
34 Nosocomial Rotovirus Gastroenetrocolitis in Children
Hospitalized Primarily Due to Respiratory Infections .................................................... 267
Aneta Nitsch-Osuch, Ernest Kuchar, Anna Kosmala,
Katarzyna Zycinska, and Kazimierz Wardyn
35 Mental Health of Polish Students and the Occurrence
of Respiratory Tract Infections .......................................................................................... 275
Sylwia Baran, Iwona Teul-Swiniarska, Edyta Dzieciolowska-Baran,
Jacek Lorkowski, and Aleksandra Gawlikowska-Sroka
36 Atherosclerotic Factors in PR3 Pulmonary Vasculitis ..................................................... 283
K. Zycinska, K. Wardyn, T.M. Zielonka, A. Nitsch-Osuch, R. Smolarczyk,
S. Zarzycki, U. Demkow, W. Lukas, and I. Pirogowicz
37 Vagal Heart Rate Control in Patients with Atrial Fibrillation:
Impact of Tonic Activation of Peripheral Chemosensory
Function in Heart Failure ................................................................................................... 287
T. Drexel, C. Eickholt, J. Mühlsteff, A. Ritz, M. Siekiera, K. Kirmanoglou,
V. Schulze, D.-I. Shin, J. Balzer, T. Rassaf, M. Kelm, and C. Meyer
38 Pulmonary Arterial Hypertension in Patients with Sarcoidosis:
The Pulsar Single Center Experience ............................................................................... 299
Stefan Pabst, Christoph Hammerstingl, Natalie Grau, Jens Kreuz,
Christian Grohe, Uwe R. Juergens, Georg Nickenig, and Dirk Skowasch
39 Cutaneous Changes: An Initial Manifestation
of Pulmonary Wegener’s Granulomatosis ........................................................................ 307
Katarzyna Zycinska, Kazimierz Wardyn, Tadeusz M. Zielonka,
Aneta Nitsch-Osuch, and Roman Smolarczyk
40 Posturography in Differential Diagnosis of Normal
Pressure Hydrocephalus and Brain Atrophy ................................................................... 311
Leszek Czerwosz, Ewa Szczepek, Beata Sokolowska, Jerzy Jurkiewicz,
and Zbigniew Czernicki
41 Psychological Background of Pro-health Behavior ......................................................... 325
Agnieszka Wilczynska, Kamilla Bargiel-Matusiewicz, Marta Troc,
and Leslaw Niebroj
42 Cardiovascular Effects of the Valsalva Maneuver During
Static Arm Exercise in Elite Power Lifting Athletes........................................................ 335
Aleksandra Zebrowska, Zbigniew Gasior, and Dariusz Jastrzebski
43 Computer Games and Fine Motor Skills .......................................................................... 343
Lukasz Borecki, Katarzyna Tolstych, and Mieczyslaw Pokorski
44 Toward the Clarification of Ideas: Medical Futility,
Persistent/Obstinate Therapy and Extra/Ordinary Means ............................................ 349
Leslaw Niebroj, Kamilla Bargiel-Matusiewicz, and Agnieszka Wilczynska
45 Psychological Attachment in Patients with Spondylosis
of Cervical and Lumbar Spine ........................................................................................... 357
Henryk Pedziwiatr
46 Fear and Anger Among Adolescents and the Behavior of Their Mothers .................... 365
Anna Jarmolowska
