Early Diagnosis and Treatment of Cancer Series: Prostate Cancer

279 Pages·2009·16.62 MB·English

by  Li-Ming Su MD

Early Diagnosis and Treatment of Cancer
Series Editor: Stephen C. Yang, MD
Breast Cancer Ovarian Cancer
Edited by Lisa Jacobs and Christina A. Finlayson Edited by Robert E. Bristow and
Deborah K. Armstrong
Colorectal Cancer
Edited by Susan Lyn Gearhart and Nita Ahuja Prostate Cancer
Edited by Li-Ming Su
Head and Neck Cancer
Edited by Wayne M. Koch
1600 John F. Kennedy Blvd.
Ste 1800
Philadelphia, PA 19103-2899
EARLY DIAGNOSIS AND TREATMENT OF CANCER: ISBN-13: 978-1-4160-4575-5
PROSTATE CANCER
Copyright © 2010 by Saunders, an imprint of Elsevier Inc. All rights reserved.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic
or mechanical, including photocopying, recording, or any information storage and retrieval system,
without permission in writing from the publisher. Details on how to seek permission, further
information about the Publisher’s permissions policies and our arrangements with organizations such as
the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website:
www.elsevier.com/permissions.
This book and the individual contributions contained in it are protected under copyright by the Publisher
(other than as may be noted herein).
Notices
Knowledge and best practice in this fi eld are constantly changing. As new research and experience
broaden our understanding, changes in research methods, professional practices, or medical
treatment may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in
evaluating and using any information, methods, compounds, or experiments described herein.
In using such information or methods they should be mindful of their own safety and the safety
of others, including parties for whom they have a professional responsibility.
With respect to any drug or pharmaceutical products identifi ed, readers are advised to check
the most current information provided (i) on procedures featured or (ii) by the manufacturer of
each product to be administered, to verify the recommended dose or formula, the method and
duration of administration, and contraindications. It is the responsibility of practitioners, relying on
their own experience and knowledge of their patients, to make diagnoses, to determine dosages and
the best treatment for each individual patient, and to take all appropriate safety precautions.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors,
assume any liability for any injury and/or damage to persons or property as a matter of products
liability, negligence or otherwise, or from any use or operation of any methods, products,
instructions, or ideas contained in the material herein.
Library of Congress Cataloging-in-Publication Data
Early diagnosis and treatment of cancer : prostate cancer / edited by Li-Ming Su.
p. ; cm.—(Early diagnosis and treatment of cancer series)
Other title: Prostate cancer
Includes index.
ISBN 978-1-4160-4575-5
1. Prostate—Cancer. I. Su, Li-Ming. II. Title: Prostate cancer. III. Series: Early diagnosis and
treatment of cancer series.
[DNLM: 1. Prostatic Neoplasms—diagnosis. 2. Prostatic Neoplasms—therapy. WJ 762 E12 2009]
RC280.P7E27 2009
616.99′463—dc22
2009009637
Acquisitions Editor: Dolores Meloni
Working together to grow
Design Direction: Steven Stave
libraries in developing countries
Printed in China. www.elsevier.com | www.bookaid.org | www.sabre.org
Last digit is the print number: 9 8 7 6 5 4 3 2 1
To my loving and supportive family: Maria, Sean, and Reilly
Series Preface
Seen on a graph, the survival rate for many ■(cid:3)What lifestyle factors might affect the
cancers resembles a precipice. Discovered at an outcome of treatment?
early stage, most cancers are quickly treatable,
Each volume in the series is edited by an
and the prognosis is excellent. In late stages,
authority within the subfi eld, and the contribu-
however, the typical treatment protocol becomes
tors have been chosen for their practical skills
longer, more intense, and more harrowing for
as well as their research credentials. Key
the patient, and the survival rate declines steeply.
Points at the beginning of each chapter help
No wonder, then, that one of the most impor-
the reader grasp the main ideas at once. Fre-
tant means in fi ghting cancer is to prevent or
quent illustrations make the techniques vivid
screen for earlier stage tumors.
and easy to visualize. Boxes and tables summa-
Within each oncologic specialty, there is a
rize recommended strategies, protocols, indica-
strong push to identify new, more useful tools
tions and contraindications, important statistics,
for early diagnosis and treatment, with an
and other essential information. Overall, the
emphasis on methods amenable to an offi ce-
attempt is to make expert advice as accessible
based or clinical setting. These efforts have
as possible to a wide variety of health care
brought impressive results. Advances in imaging
professionals.
technology, as well as the development of
For the fi rst time since the inception of the
sophisticated molecular and biochemical tools,
National Cancer Institute’s annual status reports,
have led to effective, minimally invasive
the 2008 “Annual Report to the Nation on the
approaches to cancer in its early stages.
Status of Cancer,” published in the December
This series, Early Diagnosis and Treatment of
3 issue of the Journal of the National Cancer
Cancer, gathers state-of-the-art research and
Institute, noted a statistically signifi cant decline
recommendations into compact, easy-to-use
in “both incidence and death rates from all
volumes. For each particular type of cancer, the
cancers combined.” This mark of progress
books cover the full range of diagnostic and
encourages all of us to press forward with our
treatment procedures, including pathologic,
efforts. I hope that the volumes in Early Diag-
radiologic, chemotherapeutic, and surgical
nosis and Treatment of Cancer will make health
methods, focusing on questions like these:
care professionals and patients more familiar
■(cid:3)What do practitioners need to know about the with the latest developments in the fi eld, as well
epidemiology of the disease and its risk as more confi dent in applying them, so that early
factors? detection and swift, effective treatment become
■(cid:3)How do patients and their families wade a reality for all our patients.
through and interpret the many tests they
face? Stephen C. Yang, MD
■(cid:3)What is the safest, quickest, least invasive way The Arthur B. and Patricia B. Modell
to reach an accurate diagnosis? Professor of Thoracic Surgery
■(cid:3)How can the stage of the disease be Chief of Thoracic Surgery
determined? The Johns Hopkins Medical Institutions
■(cid:3)What are the best initial treatments for early- Baltimore, Maryland
stage disease, and how should the practitioner
and the patient choose among them?