Clinical Drug Therapy: Rationales for Nursing Practice, Ninth Edition

1170 Pages·2008·19.67 MB·English

by  Anne Collins Abrams

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Clinical Drug Therapy
RATIONALES FOR NURSING PRACTICE
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CClliinniiccaall DDrruugg TThheerraappyy
RRAATTIIOONNAALLEESS FFOORR NNUURRSSIINNGG PPRRAACCTTIICCEE
Anne Collins Abrams, RN, MSN
Associate Professor, Emeritus
Department of Baccalaureate and Graduate Nursing
College of Health Sciences
Eastern Kentucky University
Richmond, Kentucky
Chapters 1-6,13-15,34-42,57,58,63-65
Carol Barnett Lammon, RN, PhD
Associate Professor
Capstone College of Nursing
University of Alabama
Tuscaloosa, Alabama
Chapters 7-10,12,16-20,26,29-33,56,59-62
Sandra Smith Pennington, RN, PhD
Professor, Emeritus
Department of Nursing
Berea College
Berea, Kentucky;
Academic Dean and Graduate Program Director, RN to MSN Program
Rocky Mountain University of Health Professions
Provo, Utah
Chapters 11,21-25,27,28,43-55
Consultant
Tracey L. Goldsmith, PharmD
Independent Legal and Healthcare Consultant
Magnolia, Texas
EDITION
9
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Acquisitions Editor:Hilarie Surrena
Managing Editor:Michelle Clarke
Senior Production Editor:Marian A. Bellus
Director of Nursing Production:Helen Ewan
Senior Managing Editor / Production:Erika Kors
Art Director, Design:Joan Wendt
Art Director, Illustration:Brett MacNaughton
Manufacturing Coordinator:Karin Duffield
Indexer:Michael Ferreira
Compositor:Spearhead
Ninth Edition
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins.
Copyright © 2007, 2004, 2001 by Lippincott Williams & Wilkins. Copyright © 1998 by Lippincott-Raven Publishers. Copyright
© 1995, 1991, 1987, 1983 by J. B. Lippincott Company. All rights reserved. This book is protected by copyright. No part of this
book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other
electronic copies, or utilized by any information storage and retrieval system without written permission from the copyright
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Printed in China
Library of Congress Cataloging-in-Publication Data
Abrams, Anne Collins.
Clinical drug therapy: rationales for nursing practice/Anne Collins Abrams, Carol Barnett Lammon, Sandra Smith
Pennington; consultant, Tracey L. Goldsmith.—9th ed.
p. ; cm.
Includes bibliographical references and index.
ISBN 978-0-7817-7769-8
1. Chemotherapy. 2. Drugs. 3. Nursing. I. Lammon, Carol Barnett. II. Pennington, Sandra Smith. III. Title.
[DNLM: 1. Pharmaceutical Preparations—Nurses’ Instruction. 2. Drug Therapy—Nurses’ Instruction. QV 55 A161c 2009]
RM262.A27 2009
615.5(cid:1)8—dc22
2008032208
Care has been taken to confirm the accuracy of the information presented and to describe generally accepted practices.
However, the authors, editors, and publisher are not responsible for errors or omissions or for any consequences from application
of the information in this book and make no warranty, expressed or implied, with respect to the currency, completeness, or accu-
racy of the contents of the publication. Application of this information in a particular situation remains the professional respon-
sibility of the practitioner; the clinical treatments described and recommended may not be considered absolute and universal
recommendations.
The authors, editors, and publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are
in accordance with the current recommendations and practice at the time of publication. However, in view of ongoing research,
changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader
is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precau-
tions. This is particularly important when the recommended agent is a new or infrequently employed drug.
Some drugs and medical devices presented in this publication have Food and Drug Administration (FDA) clearance for lim-
ited use in restricted research settings. It is the responsibility of the health care provider to ascertain the FDA status of each drug
or device planned for use in his or her clinical practice.
LWW.com
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Contributors
Susan J. Appel, Ph.D., APRN, ACNP, FNP, BC, CCRN Mary Annette Wright, RN, MSN, CRNP
Associate Professor Instructor
University of Alabama at Birmingham University of Alabama at Birmingham
Birmingham, Alabama Birmingham, Alabama
Chapter 26 Chapter 26
PatriciaB. Wolff,MSN, ACNS-BC, AOCNS
Jennifer Binggeli, PharmD, MBA
Clinical Nurse Specialist
Clinical Pharmacist
Medical Oncology
St. Petersburg, Florida
South Texas Veterans Health Care System
Chapters 29-33
Audie L. Murphy Memorial Veterans Hospital
Division
Kathleen E. Jenks, BSN, MSEd, RN San Antonio, Texas
Associate Professor Chapter 42
Mercy College of Northwest Ohio
Toledo, Ohio
Applying Your Knowledge Features
Marthe Moseley, PhD, RN, CCRN, CCNS
Clinical Nurse Specialist for Critical Care
South Texas Veterans Health Care System
Audie Murphy Hospital
San Antonio, Texas.
Chapters 49 and 51
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Reviewers
Susan Alix, RN, MS Susan Ellis-Hermansen, RN, MS
Nursing Faculty Instructor Instructor and Director of Learning Resource Center
School of Nursing University of Maine
Worcester State College Orono, Maine
Worcester, Massachusetts
Brenda L. Haile, RN, DrPH, ACRN
Debby Antonella, MSN, RN Associate Professor
Professor College of Nursing
College of Nursing Texas Woman’s University College of Nursing Houston
University of Southern Nevada Campus
Las Vegas, Nevada Houston, Texas
April Bigelow, MS, ANP-BC Nancy Hartel, MS, RN, CNE
Assistant Professor Associate Professor
Eastern Michigan University St. Joseph’s College of Nursing
School of Nursing Syracuse, New York
Ypsilanti, Michigan
Karen Hecomovich, MS, RN, BC
Jean Forsha Byrd, RN, MSN, CNE Nursing Faculty
Assistant Professor Arapahoe Community College.
Community College of Philadelphia Littleton, Colorado
Philadelphia, Pennsylvania
Kevin D. Hite, RN, MSN
Patricia W. Campbell, RN, MSN Assistant Professor of Nursing
Nursing Faculty Fairmont State University
Carolinas College of Health Sciences Fairmont, West Virginia
Charlotte, North Carolina
Jaime Huffman RN, MSN
Wendy Clark, RN, MSN
Instructor of Nursing
Assistant Professor of Nursing
Saginaw Valley State University
University of Saint Francis
University Center, Michigan
Fort Wayne, Indiana
Immaculata Igbo,MS, PhD
John F. Conklin, MSN, RN
Associate Professor
Nursing Department Chair
Prairie View A&M University
Assistant Professor of Nursing
Houston, Texas
State University of New York Canton
Michalene A. King, RN, BSN, MSEd, MSN, OhD
Ellen Cram, PhD, RN
Assistant Professor
Associate Professor, Clinical
College of Nursing
College of Nursing
University of Akron
University of Iowa
Akron, Ohio
Iowa City, Iowa
Angela J. Daniel, MSN, MBA, RN Kathie L Kochanowsky, MSN, RN, ANP-C
PhD Candidate School of Nursing Nurse practitioner
Emory University SpineCare Consultants
Atlanta, Georgia Humble, Texas
Jennifer Duhon, RN, MS Judy LaBonte M.S.N., APRN, FNP, BC
Assistant Professor of Nursing Assistant Professor
Illinois Central College Baptist College of Health Sciences
East Peoria, Illinois Memphis, Tennessee
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viii ■ Reviewers
Melissa Lambert, MSN, RN Sharon Ronaldson, RN, BSN, MEd, PhD
Assistant Professor of Nursing Nursing Instructor
St. Mary’s Center for Education Langara College
Huntington, West Virginia Vancouver, BC, Canada
John J. Leddy, Ph.D. (Pharmacology) Helene Seibert, RN, MS
Assistant Professor Nursing Education Faculty
Department of Cellular and Molecular Medicine Southwestern Illinois College
University of Ottawa Belleville, Illinois
Ottawa, ON Canada
Patty Shanaberger, RN, MSN, FNP-C
Adrianne D. Linton, PhD, RN Associate Professor
Chair and Professor, Department of Chronic Nursing Care School of Nursing
School of Nursing Professorship in Aging El Paso Community College
University of Texas at San Antonio HSC School of Nursing El Paso, Texas
San Antonio, Texas
Cordia A. Starling, RN, EdD
Janet G. Marshall, PhD, RN Professor/Dean, School of Nursing
Associate Professor Dalton State College
Florida A&M University School of Nursing Dalton, Georgia
Tallahassee, Florida
Lori Stephens, MN, RN
Kim H McAlister, MSN, RN Nursing Faculty
Instructor, Clinical Skagit Valley College Nursing Department
Department of Chronic Nursing Care Mount Vernon, Washington
UTHSCSA School of Nursing
University of Texas Health Science Center at San Antonio Judith Swanson, RN, MSN
San Antonio, Texas Assistant Professor of Nursing
Minot State University
Linda McIntosh Liptok, RN, MSN, APRN-BC Minot, North Dakota
Assistant Professor
Kent State University Tuscarawas Linda M. Tenofsky, PhD, RN, ANP-BC
New Philadelphia, Ohio Professor/Coordinator Traditional Baccalaureate Program
Department of Nursing
Edna R. Michel-Moyer, CRNP, CS Curry College
Professor of Nursing Milton, Massachusetts
The Community College of Baltimore County
Catonsville, Maryland Charlotte Thayer Wood, PhD
Professor
Jane Mighton, RN, BSN, MSN Mississippi College
Nursing Instructor, Term 4 School of Nursing
Langara College Clinton, Mississippi
Vancouver, British Columbia
Canada Melinda Wang, MSN, WHNP-BC, RN
Assistant Professor of Nursing
Luke H. Mortensen, PhD, FAHA Roane State Community College
Assistant Dean & Professor of Pharmacology and Physiology Harriman, Tennessee
Des Moines University
Des Moines, Iowa Thomas Worms, MSN, RN
Professor of Nursing
Diane E. Mosqueda, RNc, MSN, FNP-C Truman College
Nursing Faculty Chicago, Illinois
Houston Community College
Houston, Texas