Oral and Maxillofacial Pathology

985 Pages·2008·58.57 MB·English

by  Brad W. Neville

To access your Student Resources, visit:
http://evolve.elsevier.com/Neville/OMP
Evolve ® Student Learning Resources for Neville/Damm/Allen/Bouquot:
Oral and Maxillofacial Pathology, third edition, offers the following features:

• Diff erential Diagnosis of Clinical Cases
These cases include an image or images of a specifi c disease or condition. Multiple
choice questions test the student’s identifi cation skills and diagnostic competency
pertaining to the disease or condition shown. The correct answer and a rationale are
provided for each case.
• Selected Questions from Mosby’s Review for the NBDE, Part II
3 5 multiple choice questions taken from Mosby’s Review for the NBDE, Part II, are
designed to familiarize students with the format of the NBDE, Part II, examination as
well as test their oral diagnosis knowledge. Rationales are provided for the correct
answer.
• Appendix: Diff erential Diagnosis of Oral and Maxillofacial Diseases
The entire appendix as it appears in the book is included in a printable format.
• Weblinks
A variety of weblinks provides additional means of study and research.
http://evolve.elsevier.com/Neville/OMP
THIRD EDITION
BRAD W. NEVILLE,
DDS
Distinguished University Professor
Director, Division of Oral and Maxillofacial Pathology
Department of Stomatology
College of Dental Medicine
Medical University of South Carolina
Charleston, South Carolina
DOUGLAS D. DAMM,
DDS
Professor
Division of Oral and Maxillofacial Pathology
College of Dentistry
University of Kentucky
Lexington, Kentucky
CARL M. ALLEN,
DDS, MSD
Professor and Director Professor
Oral and Maxillofacial Pathology Department of Pathology
College of Dentistry College of Medicine and Public Health
The Ohio State University The Ohio State University
Columbus, Ohio Columbus, Ohio
JERRY E. BOUQUOT,
DDS, MSD
Professor and Chair Consultant in Oral Pathology
Department of Diagnostic Sciences Department of Pathology
University of Texas New York Eye and Ear Infi rmary
Dental Branch at Houston New York, New York
Houston, Texas
Adjunct Professor
Consultant in Pediatric Oral Pathology Department of Rural Health and Community
Division of Dentistry Dentistry
Pittsburgh Children’s Hospital School of Dentistry
Pittsburgh, Pennsylvania West Virginia University
Morgantown, West Virginia
11830 Westline Industrial Drive
St. Louis, Missouri 63146
ORAL AND MAXILLOFACIAL PATHOLOGY ISBN: 978-1-4160-3435-3
Third Edition
Copyright © 2009, 2002 by Saunders, an imprint of Elsevier Inc.
All rights reserved. No part of this publication may be reproduced or transmitted in any form or by
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Notice
Knowledge and best practice in this fi eld are constantly changing. As new research and experience
broaden our knowledge, changes in practice, treatment and drug therapy may become necessary
or appropriate. Readers are advised to check the most current information provided (i) on
procedures featured or (ii) by the manufacturer of each product to be administered, to verify the
recommended dose or formula, the method and duration of administration, and contraindications.
It is the responsibility of the practitioner, relying on their own experience and knowledge of the
patient, to make diagnoses, to determine dosages and the best treatment for each individual
patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the
Publisher nor the Authors assume any liability for any injury and/or damage to persons or property
arising out of or related to any use of the material contained in this book.
The Publisher
Library of Congress Cataloging-in-Publication Data
Oral and maxillofacial pathology / Brad W. Neville . . . [et al.]. — 3rd ed.
p. ; cm.
Includes bibliographical references and index.
ISBN 978-1-4160-3435-3 (hardcover : alk. paper) 1. Mouth—Diseases. 2. Teeth—Diseases.
3. Maxilla—Diseases. I. Neville, Brad W.
[DNLM: 1. Mouth Diseases—pathology. 2. Jaw Diseases—pathology. 3. Maxillofacial
Injuries—pathology. 4. Tooth Diseases—pathology. WU 140 O6253 2009]
RK307.O73 2009
617.5′2207—dc22
2008006904
Vice President and Publisher: Linda Duncan
Senior Editor: John Dolan
Developmental Editor: Courtney Sprehe
Publishing Services Manager: Patricia Tannian
Project Manager: Jonathan M. Taylor
Design Direction: Teresa McBryan
Working together to grow
libraries in developing countries
Printed in the United States of America www.elsevier.com | www.bookaid.org | www.sabre.org
Last digit is the print number: 9 8 7 6 5 4 3 2
This book is dedicated to three of our mentors:
CHARLES A. WALDRON
WILLIAM G. SHAFER
ROBERT J. GORLIN
in appreciation for all that they taught us
and in recognition of their contributions to the fi eld
of oral and maxillofacial pathology.
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Contributors
ANGELA C. CHI, DMD EDWARD E. HERSCHAFT, DDS, MA,
Assistant Professor FACD, FICD
Division of Oral and Maxillofacial Pathology Professor
Department of Stomatology Department of Biomedical Sciences
College of Dental Medicine University of Nevada–Las Vegas
Medical University of South Carolina School of Dental Medicine
Charleston, South Carolina Las Vegas, Nevada
Professor Emeritus
Department of Stomatology
THERESA S. GONZALES, DMD, MS, MS
College of Dental Medicine
Consultant in Orofacial Pain
Medical University of South Carolina
Consultant in Oral and Maxillofacial Pathology Charleston, South Carolina
Consultant in Forensic Odontology Diplomate, American Board of Forensic Odontology and
Carl R. Darnall Army Medical Center Oral Medicine
Fort Hood, Texas
Fellow, American Academy of Forensic Sciences
Diplomate, American Board of Orofacial Pain
Consulting Forensic Odontologist
Diplomate, American Board of Oral and Maxillofacial Offi ce of the Coroner/Medical Examiner, Clark County
Pathology Las Vegas, Nevada
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Preface
Oral and maxillofacial pathology is the specialty of a more in-depth discussion is provided for other condi-
dentistry and the discipline of pathology that addresses tions that affect the periodontium. In other areas, the
the nature, identifi cation, and management of diseases text offers greater detail than necessary for some
affecting the oral and maxillofacial regions. As such, it primary courses in oral and maxillofacial pathology.
occupies a unique position in the health care commu- However, because this book is also intended as a refer-
nity for both the dental and medical professions. Natu- ence source for the practicing clinician, this additional
rally, members of the dental profession (including material has been included.
general practitioners, specialists, and dental hygienists)
must have a good knowledge of the pathogenesis, clini-
NEW TO THIS EDITION
cal features, treatment, and prognosis for oral and
paraoral diseases. Likewise, such knowledge is impor- It has been seven years since the publication of the
tant for those in the medical profession, especially for second edition of this text. Although this is seemingly
physicians who specialize in such areas as otolaryngol- a short time, many signifi cant advances have been
ogy, dermatology, and pathology. made in our understanding of various oral diseases
during this period. We have added a number of new
topics, including:
ORGANIZATION
● Bisphosphonate-associated osteonecrosis
The purpose of the third edition of this text remains ● Hemangiopericytoma–solitary fi brous tumor
the same: to provide the reader with a comprehensive ● Transient lingual papillitis
discussion of the wide variety of diseases that may ● Tongue splitting and charm needles
affect the oral and maxillofacial region. Oral and Maxil- ● Hereditary mucoepithelial dysplasia
lofacial Pathology has been organized to serve as a ● Chronic ulcerative stomatitis
primary teaching text, although it should also be a ● Plasminogen defi ciency
valuable reference source for the practicing clinician. ● Oral manifestions of methamphetamine abuse
Chapters have been created that include disease pro- We also have included more than 200 new illustra-
cesses of a similar source (e.g., “Bacterial Infections,” tions in this latest edition.
“Salivary Gland Pathology,” “Bone Pathology,” “Der- This new edition features an accompanying Evolve
matologic Diseases”), because the basic understanding site. A specifi c listing of the Evolve assets for students
of pathology is facilitated by discussing diseases of a can be found in the front of the book.
similar nature at the same time. Only after attaining
this basic understanding can the clinician tackle the
ACKNOWLEDGMENTS
diffi cult task of clinical diagnosis and treatment. With
this in mind, a comprehensive appendix is included Obviously, this book could not have been accomplished
at the end of the book to help the clinician with the without the help of many individuals. We wish to thank
differential diagnosis of oral and maxillofacial disease Dr. Edward E. Herschaft, who thoroughly updated his
processes. excellent chapter on forensic dentistry. For this third
It is impossible to write a book that perfectly matches edition, we are deeply indebted to Dr. Angela C. Chi,
the requirements of every reader. Because all the who revised the chapters on Epithelial Pathology and
authors are involved in teaching, the subjects selected Bone Pathology. We are also grateful to Dr. Theresa S.
for inclusion in this text primarily refl ect what is taught Gonzales, who updated the chapter on Facial Pain and
in courses on oral and maxillofacial pathology. Al- Neuromuscular Diseases. We must thank our many
though dental caries is undeniably a common and colleagues who shared cases with us, and they have
important disease affecting the oral cavity, it is usually been credited in the legends of the illustrations.
not taught in an oral and maxillofacial pathology course; Although these individuals are too numerous to cite
rather, it is taught elsewhere in most dental schools’ here, one person in particular, Dr. George Blozis,
curricula. Therefore, we have not included a chapter deserves special recognition for his generosity in
on dental caries. Similarly, our discussion on common sharing his excellent teaching collection. We have
gingivitis and periodontitis is limited in scope, although attempted to be as thorough as possible in listing credit
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