Table Of ContentNEUROGASTROENTEROLOGY
AND
MOTILITY
Volume 18, 2006
EDITORS
Michael Schemann & Jan Tack
BLACKWELL PUBLISHING LTD
Oxford Copenhagen Melbourne Berlin Tokyo Boston Ames
NEUROGASTROENTEROLOGY
AND
MOTILITY
Contents for Volume 18
VOLUME 18 EDITORIAL
New motilin agonists: a long and winding road
NUMBER 1
T. L. Peeters
JANUARY 2006
REVIEW ARTICLE
Functional gastrointestinal disorders and mast cells: implications for
therapy
G. Barbara, V. Stanghellini, R. De Giorgio & R. Corinaldesi
ORIGINAL ARTICLES
Clinical Neurogastroenterology
Symptom responses, long-term outcomes and adverse events beyond
3 years of high-frequency gastric electrical stimulation for gastroparesis
Z. Lin, I. Sarosiek, J. Forster #2R . W. McCallum
Effect of atilmotin on gastrointestinal transit in healthy subjects:
a randomized, placebo-controlled study
M-I. Park, I. Ferber, M. Camilleri, K. Allenby, R. Trillo, D. Burton &
A. R. Zinsmeister
Removal of tonic nitrergic inhibition is a potent stimulus for human
proximal colonic propagating sequences
P. G. Dinning, M. Szczesniak @ I. J. Cook
Low-dose lactulose produces a tonic contraction in the human colon
P. Jouét, J.-M. Sabaté, E. Cuillerier, B. Coffin, M. Lémann, R. Jian &
B. Flourié
Basic Neurogastroenterology
Motility disorder in experimentally obstructed intestine: relationship
between muscularis inflammation and disruption of the ICC network
K-]. Won, T. Suzuki, M. Hori # H. Ozaki
Neural mechanisms involved in the inhibition of intestinal motility
induced by intestinal electrical stimulation in conscious dogs
S. Liu, J. Liu & J. D. Z. Chen
The hallucinogenic herb Salvia divinorum and its active ingredient
salvinorin A inhibit enteric cholinergic transmission in the guinea-pig
ileum
R. Capasso, F. Borrelli, F. Capasso, D. J. Siebert, D. J. Stewart,
J. K. Zjawiony & A. A. Izzo
Activation of peripheral 5-HT, receptors attenuates colonic sensitivity to
intraluminal distension
B. Greenwood-Van Meerveld, K. Venkova, G. Hicks, E. Dennis &
M. D. Crowell
VOLUME 18 EDITORIAL
Visceral sensation and colitis: inflammation and hypersensitivity do not
NUMBER 2
always go hand in hand
FEBRUARY 2006
K. A. Sharkey
REVIEW ARTICLE
Brain-gut connections in functional GI disorders: anatomic and
physiologic relationships
M. P. Jones, J. B. Dilley, D. Drossman & M. D. Crowell
ORIGINAL ARTICLES
Clinical Neurogastroenterology
Sensation and distribution of stress and deformation in the human
oesophagus
]. B. Frokjzr, S. D. Andersen, S. Lundbye-Christensen, P. Funch-Jensen,
A. M. Drewes & H. Gregersen
Possible role of nitric oxide in visceral hypersensitivity in patients with
irritable bowel syndrome
S. D. Kuiken, T. K. Klooker, G. N. Tytgat, A. Lei & G. E. Boeckxstaens
A multicentre study of the management of disorders of defecation in
patients with spina bifida
J. L. Lemelle, F. Guillemin, D. Aubert, J]. M. Guys, H. Lottmann,
S. Lortat-Jacob, J]. Moscovici, P. Mouriquand, A. Ruffion # M. Schmitt
Basic Neurogastroenterology
Ghrelin does not stimulate gastrointestinal motility and gastric emptying:
an experimental study of conscious dogs
T. Ohno, Y. Kamiyama, R. Aihara, T. Nakabayashi, E. Mochiki, T. Asao
@ H. Kuwano
Effects and mechanisms of long-pulse gastric electrical stimulation on
canine gastric tone and accommodation
J. H. Xing & J. D. Z. Chen
Effect of DSS-induced colitis on visceral sensitivity to colorectal
distension in mice
M. H. Larsson, L. Rapp & E. Lindstrém
Ano-rectal motility responses to pelvic, hypogastric and pudendal nerve
stimulation in the Géttingen minipig
I. S. Andersen, S. Buntzen, N. J. M. Rijkhoff, A. L. Dalmose, ]. C. Djurhuus
& S. Laurberg
CASE REPORT
Postinfectious gastroparesis related to autonomic failure: a case report
A. Lobrano, K. Blanchard, T. L. Abell, A. Minocha, W. Boone,
]. Wyatt-Ashmead, ]. Fratkin, C. Subramony, A. Wee Jr, G. Di Nardo,
G. Barbara, V. Stanghellini # R. De Giorgio
VOLUME 18 EDITORIAL
Dissecting oesophageal sensori-motor functions: the fourth domain
NUMBER 3
A. E. Bharucha
MARCH 2006
REVIEW ARTICLES
Imaging and modelling of digestion in the stomach and the duodenum
K. Schulze
Intestinal epithelial cell signalling and host-derived negative regulators
under chronic inflammation: to be or not to be activated determines the
balance towards commensal bacteria
D. Haller
ORIGINAL ARTICLES
Clinical Neurogastroenterology
Oropharyngeal dysphagia after the acute phase of stroke: predictors of
aspiration
R. Terré & F. Mearin
Distension technique influences the relationship between colonic and
rectal hypersensitivity in irritable bowel syndrome
C. Ng, A. Malcolm, R. Hansen # J. E. Kellow
Physician knowledge of Rome symptom criteria for irritable bowel
syndrome is poor among non-gastroenterologists
C. Charapata & H. Mertz
Basic Neurogastroenterology
Somatostatin receptor subtypes mediate contractility on human colonic
smooth muscle cells
V. D. Corleto, C. Severi, G. Romano, I. Tattoli, H. C. Weber,
M. Stridsberg, G. Rindi, N. Campanini, F. Tomassoni, U. Pagotto,
D. H. Coy, R. T. Jensen & G. Delle Fave
Involvement of M, muscarinic receptors in relaxant response of circular
muscle of mouse gastric antrum
T. Takeuchi, M. Toyoshima, K. Mukai, K. Hagi, M. Matsui, H. Nakajima,
Y-T. Azuma & F. Hata
Long-lasting changes in small intestinal transport following the recovery
from Trichinella spiralis infection
K. Venkova & B. Greenwood-Van Meerveld
TECHNICAL NOTE
A multimodal laser Doppler and endosonographic distension device for
studying mechanosensation and mucosal blood flow in the oesophagus
D. A. L. Hoff, H. Gregersen, S. Odegaard, L. B. Nesje, K. Oevreboe,
T. Hausken, O. H. Gilja, K. Matre & J. G. Hatlebakk
LETTER TO THE EDITOR
Response to Prof. Rosa Soares’ Letter
K-A. Gwee
VOLUME 18 REVIEW ARTICLES
From the bench to the ‘crib’-side: implications of scientific advances to
NUMBER 4
paediatric neurogastroenterology and motility
APRIL 2006
D. K. Chitkara & C. Di Lorenzo
Treatment of gastroparesis: a multidisciplinary clinical review The
American Motility Society Task Force on Gastroparesis (members in
alphabetical order)
T. L. Abell, R. K. Bernstein, T. Cutts, G. Farrugia, J. Forster, W. L. Hasler,
R. W. McCallum, K. W. Olden, H. P. Parkman, C. R. Parrish,
P. J. Pasricha, C. M. Prather, E. E. Soffer, R. Twillman & A. I. Vinik
ORIGINAL ARTICLES
Clinical Neurogastroenterology
Development of gastric slow waves and effects of feeding in pre-term and
full-term infants
]. Zhang, H. Ouyang, H. B. Zhu, H. Zhu, X. Lin, E. Co, J. Hayes &
J. D. Z. Chen
Characterization of cortical potentials evoked by oesophageal balloon
distention and acid perfusion in patients with functional heartburn
M. Yang, Z-S. Li, X-R. Xu, D-C. Fang, D-W. Zou, G-M. Xu, Z-X. Sun &
Z-X. Tu
Effects of an osmotically active agent on colonic transit
S. M. Skoog, A. E. Bharucha, M. Camilleri, D. D. Burton #@
A. R. Zinsmeister
Basic Neurogastroenterology
The effect of nitric oxide donors on nitric oxide synthase-expressing
myenteric neurones in culture
M. Zandecki, P. Raeymaekers, J. Janssens, J. Tack & P. Vanden Berghe
The P2Y, purinergic receptor expressed by enteric neurones in guinea-pig
intestine
N. Gao, H-Z. Hu, M. X. Zhu, X. Fang, S. Liu, C. Gao & J. D. Wood
Characterization of depolarization-evoked ERG K* currents in interstitial
cells of Cajal
C. M. Mckay, J. Ye & J. D. Huizinga
TECHNICAL NOTE
An energy algorithm improves symptoms in some patients with
gastroparesis and treated with gastric electrical stimulation
N. Abidi, W. L. Starkebaum & T. L. Abell
VOLUME 18 EDITORIAL
5-HT receptors and visceral hypersensitivity — 2, or not 2,, that is the
NUMBER 5
question?
MAY 2006
D. Grundy
HOT TOPIC
5-HT» , receptors do not modulate sensitivity to colonic distension in rats
with acute colorectal hypersensitivity
B. Greenwood-Van Meerveld, K. Campbell-Dittmeyer, A. C. Johnson &
G. A. Hicks
REVIEW ARTICLES
Challenges in drug development for functional gastrointestinal disorders.
Part I: Functional dyspepsia
V. Andresen & M. Camilleri
Challenges in drug development for functional gastrointestinal disorders.
Part II: Visceral pain
V. Andresen & M. Camilleri
ORIGINAL ARTICLES
Clinical Neurogastroenterology
Relationship between gastro-oesophageal reflux and gastric activity in
newborns assessed by combined intraluminal impedance, pH metry and
epigastric impedance
F. Cresi, L. Sanctis, F. Savino, R. Bretto, A. Testa & L. Silvestro
Predictors of gastric emptying in Parkinson’s disease
O. Goetze, A. B. Nikodem, ]. Wiezcorek, M. Banasch, H. Przuntek,
T. Mueller, W. E. Schmidt & D. Woitalla
Oesophago-gastric junction opening function: assessment using
ultrasound imaging and the effects of atropine
]. Liu, T. Takeda, I. Dogan, V. Bhargava & R. K. Mittal
Basic Neurogastroenterology
Efficacy and efficiency of gastric electrical stimulation with short pulses
in the treatment of vasopressin-induced emetic responses in dogs
G. Song, X. Hou, B. Yang, Y. Sun, J. Liu, W. Qian & J. D. Z. Chen
Suppression of nNOS expression in rat enteric neurones by the receptor for
advanced glycation end-products
K. Korenaga, M.-A. Micci, G. Taglialatela & P. J. Pasricha
LETTER TO THE EDITORS
The Giome project
H. Gregersen
CORRIGENDA
Corrigenda
VOLUME 18 EDITORIAL
‘Gastric’ hypoglycaemia — an important concept in diabetes management
NUMBER 6
M. Horowitz, K. L. Jones, C. K. Rayner & N. W. Read
JUNE 2006
REVIEW ARTICLE
Non-cardiac chest pain: an update
R. Fass & R. Dickman
ORIGINAL ARTICLES
Clinical Neurogastroenterology
Radial asymmetry of the upper oesophageal sphincter pressure profile: fact
or artefact
E. Bardan, M. Kern, S. Torrico, R. C. Arndorfer, B. T. Massey & R. Shaker
Proximal stomach function in obesity with normal or abnormal
oesophageal acid exposure
P. Iovino, L. Angrisani, G. Galloro, D. Consalvo, F. Tremolaterra,
A. Pascariello #® C. Ciacci
Relationships between hypoglycaemia and gastric emptying abnormalities
in insulin-treated diabetic patients
]. Lysy, E. Israeli, N. Strauss-Liviatan & E. Goldin
Intestinal sensitivity testing by transmucosal electrical nerve stimulation:
stimulus parameters to induce conscious perception
A. M. Accarino, F. Azpiroz & ].-R. Malagelada
Basic Neurogastroenterology
Evidence for a role of inducible nitric oxide synthase in gastric relaxation
of mdx mice
F. Mulé, M. G. Zizzo, A. Amato, S. Feo & R. Serio
Prokineticin 1 inhibits spontaneous giant contractions in the murine
proximal colon through nitric oxide release
W. A. Hoogerwerf
Effects of serotonin transporter inhibition on gastrointestinal motility and
colonic sensitivity in the mouse
M. D. Coates, A. C. Johnson, B. Greenwood-Van Meerveld & G. M. Mawe
TECHNICAL NOTE
Magnet Tracking: a new tool for in vivo studies of the rat gastrointestinal
motility
R. Guignet, G. Bergonzelli, V. Schlageter, M. Turini & P. Kucera
ABSTRACTS
Fourteenth International Workshop on Electrogastrography
CORRIGENDUM
Corrigendum
VOLUME 18 EDITORIAL
Neuroimmune signalling in the gut —- mediators linked to disorders?
NUMBER 7
N. Vergnolle
JULY 2006
REVIEW ARTICLES
Management of patients with chronic abdominal pain in clinical practice
M. Camilleri
Pelvic floor: anatomy and function
A. E. Bharucha
ORIGINAL ARTICLES
Clinical Neurogastroenterology
HLA and enteric antineuronal antibodies in patients with achalasia
A. Latiano, R. De Giorgio, U. Volta, O. Palmieri, C. Zagaria,
V. Stanghellini, G. Barbara, A. Mangia, A. Andriulli, R. Corinaldesi &
V. Annese
Novel smooth muscle markers reveal abnormalities of the intestinal
musculature in severe colorectal motility disorders
T. Wedel, G. J. J. M. van Eys, D. Waltregny, W. Glénisson, V. Castronovo
@ J-M. Vanderwinden
Enteroendocrine cell counts correlate with visceral hypersensitivity in
patients with diarrhoea-predominant irritable bowel syndrome
]. H. Park, P-L. Rhee, G. Kim, J. H. Lee, Y-H. Kim, J. J. Kim, ]. C. Rhee &
S. Y. Song
Validation of a semi-automated scintigraphic technique for detecting
episodic, real-time colonic flow
P. G. Dinning, E. McKay & I. J. Cook
Basic Neurogastroenterology
Intramuscular interstitial cells of Cajal associated with mast cells survive
nitrergic nerves in achalasia
N. Zarate, X. Y. Wang, G. Tougas, M. Anvari, D. Birch, F. Mearin,
].-R. Malagelada & J. D. Huizinga
Electrical activity in the rectum of anaesthetized dogs
W. J. E. P. Lammers, F. A. Abazer, L. Ver Donck, D. Smets,
J. A. J. Schuurkes & B. Coulie
Role of TNF-x in muscularis inflammation and motility disorder in a
TNBS-induced colitis model: clues from TNF-z-deficient mice
K. Kinoshita, M. Hori, M. Fujisawa, K. Sato, T. Ohama, E. Momotani &
H. Ozaki
VOLUME 18 EDITORIALS
Message from the Editors
NUMBER 8
M. Schemann, J. Szurszewski & J. Tack
AUGUST 2006
TRP channels as therapeutic targets: hot property, or time to cool down?
G. A. Hicks
REVIEW ARTICLES
Is there a role of food allergy in irritable bowel syndrome and functional
dyspepsia? A systematic review
M-I. Park & M. Camilleri
Dietary factors in functional dyspepsia
C. Feinle-Bisset #& M. Horowitz
ORIGINAL ARTICLES
Clinical Neurogastroenterology
Biomagnetic characterization of spatiotemporal parameters of the gastric
slow wave
L. A. Bradshaw, A. Irimia, ]. A. Sims, M. R. Gallucci, R. L. Palmer &
W. O. Richards
Effect of an acute intraluminal administration of capsaicin on
oesophageal motor pattern in GORD patients with ineffective
oesophageal motility
L. Grossi, G. Cappello & L. Marzio
Intragastric acidification inhibits motilin-induced phase III activity in
humans
J. J. L. Haans & A. A. M. Masclee
Basic Neurogastroenterology
Neural gastrointestinal electrical stimulation enhances colonic motility
in a chronic canine model of delayed colonic transit
C. P. Sanmiguel, S. Casillas, A. Senagore, M. P. Mintchev #
E. E. Soffer
Constitutive expression of cyclooxygenase-2 in the neuromuscular
compartment of normal human colon
N. Bernardini, R. Colucci, L. Mattii, C. Segnani, M. Fornai, R. de Giorgio,
G. Barbara, M. Castagna, V. Nardini, A. Dolfi, M. Del Tacca &
C. Blandizzi
ABSTRACTS
2006 Joint International Society Meeting in Neurogastroenterology and GI
Motility
VOLUME 18 EDITORIAL
Achalasia: botox, dilatation or laparoscopic surgery in 2006
NUMBER 9
N. Pehlivanov & P. J. Pasricha
SEPTEMBER 2006
REVIEW ARTICLE
New imaging in neurogastroenterology: an overview
M. Camilleri
ORIGINAL ARTICLES
Clinical Neurogastroenterology
Oesophageal motility disorders in type 1 diabetes mellitus and their
relation to cardiovascular autonomic neuropathy
]. F. Ascaso, B. Herreros, V. Sanchiz, I. Lluch, J. T. Real, M. Minguez,
F. Mora & A. Benages
Gastric electrical stimulation for intractable vomiting in patients with
chronic intestinal pseudoobstruction
S. Andersson, H. Lonroth, M. Simrén, G. Ringstrém, A. Elfvin &
H. Abrahamsson
Effect of a cannabinoid agonist on gastrointestinal transit and postprandial
satiation in healthy human subjects: a randomized, placebo-controlled
study
T. Esfandyari, M. Camilleri, I. Ferber, D. Burton, K. Baxter &
A. R. Zinsmeister
Postinfectious irritable bowel syndrome may occur after non-
gastrointestinal and intestinal infection
E. S. McKeown, S. D. Parry, R. Stansfield, J. R. Barton # M. R. Welfare
Basic Neurogastroenterology
Altered tachykinergic influence on gastric mechanical activity in mdx mice
F. Mulé, A. Amato, M. G. Vannucchi, M. S. Faussone-Pellegrini & R. Serio
5-HT, receptor agonists enhance both cholinergic and nitrergic activities
in human isolated colon circular muscle
S. Cellek, A. K. John, R. Thangiah, N. B. Dass, A. K. Bassil, E. M. Jarvie,
O. Lalude, S. Vivekanandan & G. J. Sanger
Plasticity of rat small intestine after removal of a chronic mechanical
obstruction
S. Bertoni, G. Gabella, V. Ballabeni, A. Ghirardi, M. Impicciatore &
E. Barocelli
VOLUME 18 EDITORIAL
A mechanical perspective on intestinal tone and gas motion
NUMBER 10
Hans Gregersen
OCTOBER 2006
REVIEW ARTICLE
Advances in ontogeny of the enteric nervous system
A. J. Burns & N. Thapar
ORIGINAL ARTICLES
Clinical Neurogastroenterology
Gastro-oesophageal reflux of liquids and gas during transient lower
oesophageal sphincter relaxations
A. J. Bredenoord, B. L. A. M. Weusten, R. Timmer & A. J. P. M. Smout
Regional gastric emptying abnormalities in functional dyspepsia and
gastro-oesophageal reflux disease
S. Gonlachanvit, A. H. Maurer, R. S. Fisher # H. P. Parkman
Intestinal tone and gas motion
F. Tremolaterra, A. Villoria, ]. Serra, F. Azpiroz & J.-R. Malagelada
Effect of female sex hormone supplementation and withdrawal on
gastrointestinal and colonic transit in postmenopausal women
]. Gonenne, T. Esfandyari, M. Camilleri, D. D. Burton, D. A. Stephens,
K. L. Baxter, A. R. Zinsmeister & A. E. Bharucha
The influence of the novel 5-HT,, agonist R137696 on the proximal
stomach function in healthy volunteers
G. E. Boeckxstaens, G. N. Tytgat, E. Wajs, L. Van Nueten, F. De Ridder,
A. Meulemans & J. Tack
Basic Neurogastroenterology
The nocturnal jejunal migrating motor complex: defining normal ranges
by study of 51 healthy adult volunteers and meta-analysis
S. M. Scott, C. H. Knowles, D. Wang, E. Yazaki, L. Picon, D. L. Wingate &
G. Lindberg
Hyperexcitability of convergent colon and bladder dorsal root ganglion
neurons after colonic inflammation: mechanism for pelvic organ cross-
talk
A. P. Malykhina, C. Qin, B. Greenwood-Van Meerveld, R. D. Foreman,
F. Lupu & H. I. Akbarali
Involvement of cannabinoid receptors in inflammatory hypersensitivity to
colonic distension in rats
M. Sanson, L. Bueno & J. Fioramonti
VOLUME 18 EDITORIAL
Serotonin transporter gene polymorphisms in irritable bowel syndrome
NUMBER 11
B. Geeraerts, L. Van Oudenhove & J. Tack
NOVEMBER 2006
REVIEW ARTICLE
Electrical stimulation — an evolving concept in the treatment of colonic
motor dysfunctions
C. Sevcencu
ORIGINAL ARTICLES
Clinical Neurogastroenterology
Assessment of oesophageal emptying in achalasia patients by intraluminal
impedance monitoring
J. M. Conchillo, M. Selimah, A. J]. Bredenoord, M. Samsom &
A. J. P. M. Smout
Ambulatory 24-h oesophageal impedance-pH recordings: reliability of
automatic analysis for gastro-oesophageal reflux assessment
S. Roman, S. Bruley des Varannes, P. Pouderoux, U. Chaput, F. Mion,
J.-P. Galmiche & F. Zerbib, Consortium de Recherche Indépendant sur le
Traitement et I’Exploration du Reflux gastro-oesophagien et de
l’Endobrachyoesophage (CRITERE)
Relationship between upper gastrointestinal symptoms and changes in
body weight in a population-based cohort
F. Cremonini, G. R. Locke III, C. D. Schleck, A. R. Zinsmeister &@
N. J. Talley
Serotonin transporter gene polymorphism and irritable bowel syndrome
]. M. Park, M.-G. Choi, J.-A. Park, J]. H. Oh, Y. K. Cho, I. S. Lee, S. W. Kim,
K. Y. Choi & I.-S. Chung
Influence of alcohol consumption on IBS and dyspepsia
S. L. 8. Halder, G. R. Locke, C. D. Schleck, A. R. Zinsmeister &
N. J. Talley
Basic Neurogastroenterology .
Vasoactive intestinal peptide receptor subtypes and signalling pathways
involved in relaxation of human stomach
C. Severi, I. Tattoli, V. D. Corleto, M. A. Maselli, P. Trisolini # G. Delle
Fave
Different susceptibilities of spontaneous rhythmicity and myogenic
contractility to intestinal muscularis inflammation in che hapten-
induced colitis
M. Kiyosue, M. Fujisawa, K. Kinoshita, M. Hori & H. Ozaki
Supraspinal control of external anal sphincter motility: effects of vesical
distension in humans and cats
V. Vitton, J.-C. Grimaud, M. Bouvier & A. Abysique
LETTERS TO THE EDITORS
MRI of the stomach in neurogastroenterology
J. J. L. Haans & A. A. M. Masclee
Response to letter from Dr Haans and Professor Masclee
M. Camilleri
