A Survey of Cell Biology [Vol 167] - K. Jeon (AP, 1996) WW

335 Pages·1996·19.21 MB·English

VOLUME 167

SERIES EDITORS

Geoffrey H. Bourne
1949-1 988

Martin Friedlander
1984-1 992

James F. Danielli
1949-1 984
Kwang W. Jeon
1967-

Jonathan Jarvik
1993-1 995

EDITORIAL ADVISORY BOARD

Aimee Bakken
Eve Ida Barak
Howard A. Bern
Robert A. Bloodgood
Dean Bok
Stanley Cohen
Rene Couteaux
Marie A. DiBerardino
Charles J. Flickinger
Nicholas Gillham
Elizabeth D. Hay
P. Mark Hogarth
Anthony P. Mahowald
M. Melkonian
Keith E. Mostov
Audrey L. Muggleton-Harris

Andreas Oksche
Muriel J. Ord
Vladimir R. Pantic
Thomas D. Pollard
L. Evans Roth
Jozef St. Schell
Manfred Schliwa
Hiroh Shibaoka
Wilfred 0. Stein
Ralph M. Steinman
M. Tszawa
Yoshio Watanabe
Donald P. Weeks
Robin Wright
Alexander L. Yudin

International Review of
Cytology

Edited by

Kwang W. Jeon
Department of Zoology
University of Tennessee
Knoxville, Tennessee

VOLUME 167

ACADEMIC PRESS
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Front cover photograph: Electron micrograph of reassembled coats formed on
dialysis of total pea clathrin-coated vesicle coat proteins showing distinct
polygonal lattice structure. (See Chapter I for more details.)

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CONTENTS

Contributors
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
ix

Clathrin-Coated Vesicles in Plants
Leonard Beevers

I. Historical Background
. . . . . . . . . .
. . . . . . . . . .

. . . . . . . . . . . . .
. . . . . . . . . .
. . . . . . . . . . . . . . . .
. . . . . . . . . .

VH.
Prospects and Unresolved Problems
.................
..........
. . . . . . . . . . . . .
................................

Peptides in the Nervous Systems of Cnidarians:
Structure, Function, and Biosynthesis
Cornelis J. P. Grimrnelikhuijzen, Ilia Leviev, and Klaus Carstensen

II. Anatomy of the Cnidarian Nervous System ..................................
I I I.
Neurotransmission . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

IV.
Neuropeptides . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

V.
Peptide Receptors . . . . . . . . . . . . .
. . . . . . . . . . .
. . . . . . . . . . . .

VI.
Biosynthesis of Neuropeptides
. . . . . . . . . .

VII.
Discussion
. . . . . . . . . . . . .
. . . . . . . . . .

VIII.
Perspective

References
. . . . . . . . . .

1

2

10

22

23
26

a

2a

3a

39
42

43
55
57

77

82

83

CONTENTS
vi

I.
II.
Ill.

IV.

V.

VI.
VII.

I.
II.
Ill.

IV.

V.

M Cells in Peyer’s Patches of the Intestine

Andreas Gebert, Hermann-Josef Rothkotter, and Reinhard Pabst

Introduction . . , . , , . , , . . . . . , , , , , , . , , , ,

Lymphoid Cells in the Gut Wall. . . , . . , , , ,

Dome Epithelium , , . , , . . . . . . . . . , , , , , , ,
M Cells , , , , . , , , . , , . . . . . . . . . . . . , , , , ,

Other Cells of the Dome Epithelium , , , . , ,

M Cells at Locations Outside the Gut . . , , .

Clinical Relevance and Perspectives . . , , ,

References . . . . . . . . . . . . . , , . . . . . , , , , , . . . . . . . . . . . . . . . , , .

pp’l 25FAK
in the Focal Adhesion

Carol A. Otey

Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Regulation of FAK Activity . . . . . , , , , , , , . . . . . . . , . , . , . , . . . . .

Downstream Effects of FAK . . . . . . . . . . , , . . . , . , . . . . . . . . . . . .

Concluding Remarks , . . . . . . . . . . . . . . . . , . . . . . . . . . . . . . . . . . .
References
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . .

...........................
. . . . . . . .

91

92

99
111

130

135

138
144

161

165

168
1 72

178

179

Feedback Inhibitors in Normal and Tumor Tissues

E. Marshall and B. I. Lord

I. Introduction
...................................
. . . . . . . .
185

II.
Feedback Inhibition , , . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . .
192

IV.
Inhibitors of Hemopoietic Stem Cell Proliferation . . . . . . . . . . . . . .

V.
Feedback Regulators and Tumor Tissues . . . . . . , , . , , , , , . . . . . . . . . . . . . . . . . . . . .
232

VI.
Clinical Perspectives , . . . . . . . . . . . . . . . . . . . . . . . . . , , , . , . . . . . . . . . . . . . . . . . . . . .
238

VII.
Concluding Remarks , . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . .
243
References
...................................
. . .
244

. . . . . . . . . . . . . .
I
.
.
.
.
............ . . . ,

The Incidence, Origin, and Etiology of Aneuploidy

Darren K. Griffin

I.
Introduction , , , , . , , , . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
II. Incidence., , , , , , , , , . , , , .. , , . , , , , , , , , . , , , . , , , , . , , . . . . . . . . . . . , . , , , , , , , , ,

263

265

CONTENTS
vii

. . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . .

VI.
Concluding Remarks

Index , , . . , . . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . , .. .
297

This Page Intentionally Left Blank

Numbers in parentheses indicate the pages on which the authors' contributions begin

Leonard Beevers (I ), Department of Botany and Microbiology, University of Oklahoma,

Klaus Carstensen, (37), Department of Cell Biology andAnatomy, University of Copen-

Andreas Gebert, (91), Center of Anatomy, Hannover Medical School, 0-30623

Darren K. Griffin (263), Department of Genetics and Center for Human Genetics, Case

Cornelis J. P. Grimmelikhuijzen (37), Department of Cell BiologyandAnatomy, Univer-

Ilia Leviev (37), Department of Cell Biology and Anatomy, University of Copenhagen,

B. I. Lord (1 85) , CRC Department of Experimental Haematology, Paterson Institute

E. Marshall (1 85), Department of Medical Oncology, Christie Hospital, NHS Trust,

Carol A. Otey (161), Department of Cell Biology, School of Medicine, University of

Reinhard Pabst (91), Center of Anatomy, Hannover Medical School, 0-30623

Hermann-Josef Rothkotter (91), Center of Anatomy, Hannover Medical School,

Norman, Oklahoma 730 19

hagen, DK-2100 Copenhagen .S; Denmark

Hannover, Germany

Western Reserve University, Cleveland, Ohio 44 106-4955

sity of Copenhagen, DK-2100 Copenhagen .S; Denmark

DK-2100 Copenhagen .S; Denmark

for Cancer Research, Manchester M20 9BX, United Kingdom

Manchester M20 9BX, United Kingdom

Virginia, Charlottesville, Virginia 22908

Hannover, Germany

0-30623 Hannover, Germany

ix